Lysyl Oxidase (LOX) Antibody | EMD Millipore ABT112 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Lysyl Oxidase (LOX) Antibody

catalog :

ABT112

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:400	Kaku M, Rosales Rocabado J, Kitami M, Ida T, Akiba Y, Yamauchi M, et al. Mechanical Loading Stimulates Expression of Collagen Cross-Linking Associated Enzymes in Periodontal Ligament. J Cell Physiol. 2016;231:926-33 pubmed publisher

product information

Catalog Number :

ABT112

Subcategory :

Cell Structure

Product Name :

Anti-Lysyl Oxidase (LOX) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P28300

Host Name :

Rabbit

Antigen :

Lysyl Oxidase (LOX)

Conjugate :

Affinity Purified

Product Description :

Anti-Lysyl Oxidase (LOX) Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

Lysyl Oxidase (Protein-lysine 6-oxidase; LOX) is a member of the lysyl oxidase family and a product of the LOX gene. Lysyl oxidase is an extracellular-matrix oxidative enzyme characterized by its C-terminal LOX catalytic domain. In the presence of copper, lysyl oxidase removes amine groups from lysine residues of target substrates which include precursors of collagen and elastin. This deamination reaction produces reactive lysine residues which can then interact with similarly activated species to form covalent cross-links. Lysyl oxidase is found predominantly in the kidney, pancreas, heart, skeletal muscle, and placenta. Defective lysyl oxidase proteins play a role in cutis laxa autosomal recessive type 1 condition. Other studies have also suggested that lysyl oxidase may also be involved in intracellular signaling and may function as a tumor suppressor.

ALT Names :

Protein-lysine 6-oxidase;Lysyl oxidase

Immunogen :

KLH-conjugated linear peptide corresponding to Lysyl Oxidase (LOX).

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt