Tks5, PX domain Antibody | EMD Millipore ABT102 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Tks5, PX domain Antibody

catalog :

ABT102

quantity :

100 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, immunoprecipitation

product information

Catalog Number :

ABT102

Subcategory :

Cell Structure

Product Name :

Anti-Tks5, PX domain Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q5TCZ1

Host Name :

Rabbit

Antigen :

Tks5

Conjugate :

Affinity Purified

Product Description :

Anti-Tks5, PX domain Antibody

Cross Reactivity :

Mouse

Background :

Tks5 (previously known as Fish), is a large scaffolding protein with one amino-terminal PX domain and five SH3 domains. It is cytoplasmic in normal fibroblasts. In Src-transformed cells, Tks5 localizes to podosomes. The coexpression of Tks5 and constitutively active Src in epithelial cancer cells resulted in the appearance of podosomes/invadopodia. Cells with reduced Tks5 expression are poorly invasive through matrigel. Tks5 is expressed and localized to podosomes/invadopodia in some invasive human cancer cell lines and tumor tissue, particularly breast cancers and melanomas. Thus, Tks5 appears to be required for podosome/invadopodia formation and for invasion of some cancer cells.

ALT Names :

SH3 and PX domain-containing protein 2A;Adapter protein TKS5;Five SH3 domain-containing protein;SH3 multiple domains protein 1;Tyrosine kinase substrate with five SH3 domains

Immunogen :

KLH-conjugated linear peptide corresponding to the PX domain of human Tks5.

Specificity :

This antibody specifically recognizes the PX domain of Tks5.

Package Size :

100 µL

Uses :

Western Blotting;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt