phospho LEF Antibody (Thr155) | EMD Millipore ABS485 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho LEF Antibody (Thr155)

catalog :

ABS485

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

western blot

product information

Catalog Number :

ABS485

Subcategory :

Cell Signaling

Product Name :

Anti-phospho LEF Antibody (Thr155)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9UJU2

Host Name :

Rabbit

Antigen :

phospho LEF (Thr155)

Conjugate :

Affinity Purified

Product Description :

Anti-phospho LEF Antibody (Thr155)

Cross Reactivity :

Human

Background :

Lymphoid enhancer factor, LEF-1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF-1, TCF-1, TCF-3, and TCF-4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma, and breast cancer. LEF-1 is expressed during development in many different differentiating tissues, and in a few tissues after birth. LEF-1 expression is required for proper development of breast, teeth, hair, whiskers, and the trigeminal nerve.

ALT Names :

Lymphoid enhancer-binding factor 1;LEF-1;T cell-specific transcription factor 1-alpha;TCF1-alpha;TCF1A

Immunogen :

KLH-conjugated linear peptide corresponding to the Proline Rich Domain of human LEF1 phosphorylated at Thr155.

Package Size :

100 μg

Uses :

Western Blotting;Peptide Inhibition Assay

Storage :

Stable for 1 year at 2-8°C from date of receipt