MAPK 1/2 Antibody | EMD Millipore ABS44 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MAPK 1/2 Antibody

catalog :

ABS44

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 3b	Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester BeltrÃ¡n J, et al. Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest. 2017;127:814-829 pubmed publisher
	Notarangelo T, Sisinni L, Condelli V, Landriscina M. Dual EGFR and BRAF blockade overcomes resistance to vemurafenib in BRAF mutated thyroid carcinoma cells. Cancer Cell Int. 2017;17:86 pubmed publisher

product information

Catalog Number :

ABS44

Subcategory :

Cell Signaling

Product Name :

Anti-MAPK 1/2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P21708

Host Name :

Rabbit

Antigen :

MAPK 1/2

Conjugate :

Purified

Product Description :

Anti-MAPK 1/2 Antibody

Cross Reactivity :

Rat;Mouse;Human

Background :

The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called MAPK1 and MAPK2, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or MAPK1/2. The MAPK1/2 signaling cascade has been shown to be a critical regulator of cell differentiation, cell physiology and neuronal function. Aberrant control of MAPK1/2 activity has been implicated in a variety of pathological conditions, including cancer and autoimmune diseases, and efficient study methods are in demand.

ALT Names :

Extracellular signal-regulated kinase 2;MAP kinase 2;MAPK 2;Mitogen-activated protein kinase 2;extracellular signal-regulated kinase-2;mitogen-activated protein kinase 1;protein tyrosine kinase ERK2

Immunogen :

KLH-conjugated linear peptide corresponding to rat MAPK 1/2 at the C-terminus.

Specificity :

This antibody recognizes MAPK1/2 at the C-terminus.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt