PDE4D Antibody | EMD Millipore ABS22 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PDE4D Antibody

catalog :

ABS22

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chimpanzee

application :

western blot, immunohistochemistry - free floating section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:1000; loading ...; fig 7b	Katrancha S, Shaw J, Zhao A, Myers S, Cocco A, Jeng A, et al. Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits. Cell Rep. 2019;26:2805-2817.e9 pubmed publisher
western blot; human; 1:1000; loading ...; fig s12c	Carlyle B, Kitchen R, Kanyo J, Voss E, Pletikos M, Sousa A, et al. A multiregional proteomic survey of the postnatal human brain. Nat Neurosci. 2017;20:1787-1795 pubmed publisher
immunohistochemistry - free floating section; rat; 2 ug/ml; fig 3	Wilson N, Titus D, Oliva A, Furones C, Atkins C. Traumatic Brain Injury Upregulates Phosphodiesterase Expression in the Hippocampus. Front Syst Neurosci. 2016;10:5 pubmed publisher

product information

Catalog Number :

ABS22

Subcategory :

Cell Signaling

Product Name :

Anti-PDE4D Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q08499

Host Name :

Rabbit

Antigen :

PDE4D

Conjugate :

Purified

Product Description :

Anti-PDE4D Antibody

Cross Reactivity :

Rat;Human;Chimpanzee

Background :

Phosphodiesterase 4D (PDE4D) is a member of the PDE cyclic nucleotides. PDE4D is known to be regulated by protein kinase C (PKC)-Raf-MEK-ERK and also by cAMP in vascular smooth muscle cells. PDE4D is essential to have equilibrium in relaxing and contracting cues to airway smooth muscle. Down-regulation of PDE4D may be associated with analgesic and anti-inflammatory effects. It has also been linked to the risk of stroke, specifically common polygenic stroke.

ALT Names :

phosphodiesterase 4D, cAMP-specific;cAMP-specific phosphodiesterase PDE4D6;cAMP-specific 3',5'-cyclic phosphodiesterase 4D;phosphodiesterase 4D, cAMP-specific (dunce (Drosophila)-homolog phosphodiesterase E3);phosphodiesterase 4D, cAMP-specific (dunce);phosphodiesterase E3 dunce homolog;phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila);dunce-like phosphodiesterase E3;cAMP-specific phosphodiesterase 4D

Immunogen :

GST-tagged recombinant protein corresponding to the C-terminus of human PDE4D.

Specificity :

This antibody recognizes PDE4D at the C-terminus.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt