Rab27B Antibody | EMD Millipore ABS1026 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rab27B Antibody

catalog :

ABS1026

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 3b	Li Z, Scott M, Brzoska T, Sundd P, Li Y, Billiar T, et al. Lung epithelial cell-derived IL-25 negatively regulates LPS-induced exosome release from macrophages. Mil Med Res. 2018;5:24 pubmed publisher
	Nojima H, Konishi T, Freeman C, Schuster R, Japtok L, Kleuser B, et al. Chemokine Receptors, CXCR1 and CXCR2, Differentially Regulate Exosome Release in Hepatocytes. PLoS ONE. 2016;11:e0161443 pubmed publisher

product information

Catalog Number :

ABS1026

Subcategory :

Cell Signaling

Product Name :

Anti-Rab27B Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O00194

Host Name :

Rabbit

Antigen :

RAB27B

Conjugate :

Serum

Purification Method :

Unpurified

Product Description :

Anti-Rab27B Antibody

Cross Reactivity :

Mouse, Human, Rat

Background :

RAB27B, also known as C25KG, is a member of the Rab GTPase superfamily. RAB27B acts as a lipid anchoring protein that is prenylated and works in vesicular fusion and protein trafficking within cells. The protein is most highly expressed in testis but can be expressed in other cell types as well. Because Rab27B is widely expressed in various tissues together with Rab27A and RAB27B has been found to have the ability to bind all of the Rab27A effectors that have been tested, Rab27A and Rab27B were initially thought to function redundantly by sharing common Rab27 effectors. However, recent evidence has indicated that by interacting with different Rab27 effectors Rab27A and Rab27B play different roles in special types of secretion (e.g. exosome secretion and mast cell secretion) even within the same cell type. Rab27B is particularly important for regulating protein secretion by pancreatic acinar cells, for instance.

ALT Names :

Ras-related protein Rab-27B, C25KG

Immunogen :

GST-tagged recombinant protein corresponding to human Rab27B.

Package Size :

100 µL

Uses :

Western Blotting, Immunoprecipitation, Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.