phospho-NR1 (Ser896) Antibody | EMD Millipore ABN88 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-NR1 (Ser896) Antibody

catalog :

ABN88

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:3000; fig 6	Posa L, Accarie A, Noble F, Marie N. Methadone Reverses Analgesic Tolerance Induced by Morphine Pretreatment. Int J Neuropsychopharmacol. 2016;19: pubmed publisher
	De Felice M, Lambert D, Holen I, Escott K, Andrew D. Effects of Src-kinase inhibition in cancer-induced bone pain. Mol Pain. 2016;12: pubmed publisher

product information

Catalog Number :

ABN88

Subcategory :

Neuroscience

Product Name :

Anti-phospho-NR1 (Ser896) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P35439

Host Name :

Rabbit

Antigen :

phospho-NR1 (Ser896)

Conjugate :

Affinity Purified

Product Description :

Anti-phospho-NR1 (Ser896) Antibody

Cross Reactivity :

Rat;Human;Mouse

Background :

NR1 (NMDA1or NMDAR1, also known as GRIN1) along with the NR2 subunit forms a heterodimer that make up the NMDA receptor. The NMDA receptor (NMDAR) is characterized as a ionotropic receptor for glutamate. As the name suggests, (NMDA (N-methyl D-aspartate) is an agonist for the receptor. A distinct characteristic of the NMDA receptor is that it is both ligand-gated and voltage-dependent based on its sensitivity to magnesium. Activated NMDA receptors result in the opening of an ion channel that is nonselective to cations. The result is the flow of Na+ and small amounts of Ca2+ ions into the cell and K+ out of the cell. Calcium flux by the NMDARs has been implicated in synaptic plasticity, a mechanism in the cell for learning and memory.

ALT Names :

glutamate receptor, ionotropic, N-methyl D-aspartate 1;glutamate [NMDA] receptor subunit zeta 1;N-methyl-D-aspartate receptor channel, subunit zeta-1;N-methyl-D-aspartate receptor subunit NR1;glutamate [NMDA] receptor subunit zeta-1

Immunogen :

KLH-conjugated linear peptide corresponding to rat NR1 phosphorylated at Ser896.

Specificity :

This antibody recognizes NR1 when phosphorylated at Ser896.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt