CAPS-2 Antibody | EMD Millipore ABN326 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CAPS-2 Antibody

catalog :

ABN326

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; fig s4a	Feng W, Kawauchi D, Körkel Qu H, Deng H, Serger E, Sieber L, et al. Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. Nat Commun. 2017;8:14758 pubmed publisher

product information

Catalog Number :

ABN326

Subcategory :

Neuroscience

Product Name :

Anti-CAPS-2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q86UW7

Host Name :

Rabbit

Antigen :

CAPS-2

Conjugate :

Affinity Purified

Product Description :

Anti-CAPS-2 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

CAPS-2 and the related protein CAPS-1 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficient neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. Like CAPS-1, numerous isoforms of CAPS-2 are known to exist. These isoforms show distinct expression patterns in the brain. For example, CAPS2b showed high expression in the developing cerebellum. Furthermore, one version of CAPS-2 mRNA that lacks exon 3 is detected in some autistic patients, suggesting that the differential expression pattern of CAPS-2 is involved in neuronal development.

ALT Names :

Calcium-dependent secretion activator 2;CADPS2;CAPS-2

Immunogen :

KLH-conjugated linear peptide corresponding to human CAPS-2.

Specificity :

This antibody is predicted to be specific to CAPS-2 and not recognize CAPS-1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt