Rhes Antibody | EMD Millipore ABN31 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rhes Antibody

catalog :

ABN31

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1a western blot; mouse; fig 1a	Shahani N, Swarnkar S, Giovinazzo V, Morgenweck J, Bohn L, Scharager Tapia C, et al. RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Sci Signal. 2016;9:ra111 pubmed

product information

Catalog Number :

ABN31

Subcategory :

Neuroscience

Product Name :

Anti-Rhes Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q96D21

Host Name :

Rabbit

Antigen :

Rhes

Conjugate :

Affinity Purified

Product Description :

Anti-Rhes Antibody

Cross Reactivity :

Human;Mouse;Rat;Rhesus Macaque

Background :

Ras family proteins are molecular switches, which are mediated by extracellular signals and regulate intracellular signaling pathways, thereby controlling a plethora of biological functions such as cell growth, gene transcription, mRNA stability and translation, cytoskeleton organization, peptide trafficking and secrection. Ras proteins are also involved in synaptic plasticity, learning, and memory in the central nervous system. As a member of the RASD subfamily of the Ras-related GTP-binding protein superfamily, Rhes is predominantly expressed in the striatal region of the brain, where it reported to influence brain development and function. It is thought that the activation and expression of the Rhes gene is mediated by thyroid hormones in the brain. In humans, a lack of such hormones is known to cause cretinism. Additionally, Rhes -/- knockout mice display marked behavioral abnormalities, a gender-dependent increase in anxiety levels, and a clear deficit in motor coordination.

ALT Names :

GTP-binding protein Rhes;Ras homolog enriched in striatum;Tumor endothelial marker 2

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human Rhes.

Specificity :

This antibody recognizes the C-terminus of Rhes.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt