PTGDS Antibody | EMD Millipore ABN253 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PTGDS Antibody

catalog :

ABN253

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, Rhesus monkey

application :

western blot, immunohistochemistry

product information

Catalog Number :

ABN253

Subcategory :

Neuroscience

Product Name :

Anti-PTGDS Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P41222

Host Name :

Rabbit

Antigen :

PTGDS

Conjugate :

Purified

Product Description :

Anti-PTGDS Antibody

Cross Reactivity :

Human;Rhesus Macaque

Background :

Prostaglandin-H2 D-isomerase (PTGDS), also known the Lipocalin-type prostaglandin-D synthase, catalyzes the conversion of PGH2 to PGD2. PTGDS serves both as a PGD2-synthesizing enzyme and as an extracellular transporter of various lipophilic small molecules. It is the only enzyme in the lipocalin type protein family, members of which mainly act as binding proteins. It has been shown to bind various small, lipophilic compounds such as retinoic acid, biliverdin, bilirubin, retinoic acid, and thyroid hormone and may act as a scavenger for harmful hydrophobic molecules. In cells it is localized in the endoplasm reticulum, golgi apparatus, cell membrane, and is also secreted. PTGDS is involved in several central nervous system functions, such as sedation, pain regulation and non-rapid eye movement sleep. It is suggested to be involved in development and maintenance of the blood-brain, blood-retina, and blood-aqueous humor barriers and may also play a role in maturation and maintenance of the central nervous system.

ALT Names :

Prostaglandin-H2 D-isomerase;Beta-trace protein;Cerebrin-28;Glutathione-independent PGD synthase;Lipocalin-type prostaglandin-D synthase;Prostaglandin-D2 synthase;PGD2 synthase;PGDS;PGDS2

Immunogen :

KLH-conjugated linear peptide corresponding to human PTGDS.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt