Dopamine D(1A) Receptor Antibody | EMD Millipore ABN20 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Dopamine D(1A) Receptor Antibody

catalog :

ABN20

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

rat, bovine

application :

western blot, ELISA, immunohistochemistry

citations: 1

Reference
Socodato R, Santiago F, Portugal C, Domith I, Encarnação T, Loiola E, et al. Dopamine promotes NMDA receptor hypofunction in the retina through D1 receptor-mediated Csk activation, Src inhibition and decrease of GluN2B phosphorylation. Sci Rep. 2017;7:40912 pubmed publisher

product information

Catalog Number :

ABN20

Subcategory :

Neuroscience

Product Name :

Anti-Dopamine D(1A) Receptor Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P18901

Host Name :

Rabbit

Antigen :

Dopamine D(1A) Receptor

Conjugate :

Affinity Purified

Product Description :

Anti-Dopamine D(1A) Receptor Antibody

Cross Reactivity :

Rat;Bovine

Background :

Dopaminergic signals are thought to modulate corticostriatal synapses onto medium spiny projection neurons, and this plasticity is, in turn, thought to alter patterns of activity during learning. Subversion of these processes in clinical and rodent models is hypothesized to contribute importantly to addiction to psychostimulants, seizures, and movement disorders in Huntington’s (HD) and Parkinson’s disease (PD). Dopamine receptor D1, also known as DRD1, is the most abundant dopamine receptor (of the five types D1-D5) in the central nervous system and is critically involved in these processes and the modulation of D2 receptor mediated events. Coupled with G-protein, the D1a receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases including the key molecular switch, DARPP-32.

ALT Names :

dopamine receptor D1, D(1A) dopamine receptor

Immunogen :

KLH-conjugated linear peptide of rat dopamine D(1A) receptor at and around the cytoplasmic domain.

Specificity :

This antibody recognizes D(1A) dopamine receptor.

Package Size :

100 μg

Uses :

Immunohistochemistry;Western Blotting;ELISA

Storage :

Stable for 1 year at 2-8°C from date of receipt