alpha B-crystallin Antibody | EMD Millipore ABN185 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

alpha B-crystallin Antibody

catalog :

ABN185

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, bovine

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 1b western blot; mouse; 1:1000; loading ...; fig 1a	Lim E, Nakanishi S, Hoghooghi V, Eaton S, Palmer A, Frederick A, et al. AlphaB-crystallin regulates remyelination after peripheral nerve injury. Proc Natl Acad Sci U S A. 2017;114:E1707-E1716 pubmed publisher
immunohistochemistry - paraffin section; human; 1:2000; loading ...; fig 6	Noy S, Krawitz S, Del Bigio M. Chronic Traumatic Encephalopathy-Like Abnormalities in a Routine Neuropathology Service. J Neuropathol Exp Neurol. 2016;75:1145-1154 pubmed publisher

product information

Catalog Number :

ABN185

Subcategory :

Neuroscience

Product Name :

Anti-alpha B-crystallin Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P02511

Host Name :

Rabbit

Antigen :

alpha B-crystallin

Conjugate :

Affinity Purified

Product Description :

Anti-alpha B-crystallin Antibody

Cross Reactivity :

Bovine;Human;Rat;Mouse;Ox;Horse;Rhesus Macaque

Background :

Alpha B-crystallin is a major structural protein in the vertebrate eye lens, but is also found in cardiac and skeletal muscles, kidney, and brain. Alpha B-crystallin is also found to be a component of Rosenthal fibers and a consistent tissue marker of epileptic foci. It occurs as large aggregates of up to 106 Da, composed of two proteins, αA- and αB-crystallin. The αA gene encodes a polypeptide of 173 residues, while αB-crystallin gene encodes a 175 residue polypeptide. αB-crystallin, like the small heat shock proteins (sHsp's), is induced by heat or osmotic shock and is upregulated by stress. α-crystallin and the sHsp's protect other proteins from heat-induced aggregation. The two other crystallin families, β and ɣ, are homologous to each other but not to the α-family or the sHsp's.

ALT Names :

Alpha-crystallin B chain;Alpha(B)-crystallin;Heat shock protein beta-5;Renal carcinoma antigen NY-REN-27;Rosenthal fiber component

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus human alpha B-crystallin.

Specificity :

This antibody recognizes the N-terminus of alpha B-crystallin.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt