CYP27B1 Antibody | EMD Millipore ABN182 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CYP27B1 Antibody

catalog :

ABN182

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry

product information

Catalog Number :

ABN182

Subcategory :

Neuroscience

Product Name :

Anti-CYP27B1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O15528

Host Name :

Rabbit

Antigen :

CYP27B1

Conjugate :

Affinity Purified

Product Description :

Anti-CYP27B1 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

25-hydroxyvitamin D-1 alpha hydroxylase (1αOHase; VD3 1A hydroxylase; 25-OHD-1 alpha-hydroxylase; 25-hydroxyvitamin D(3) 1-alpha-hydroxylase; or CYP27B1) is a mitochondrial enzyme that belongs to the cytochrome P450 family. It catalyzes the hydroxylation of 25-hydroxyvitamin D3 to form an active 1-alpha, 25-dihydroxyvitamin D3, in the kidneys and other tissues. 25-hydroxyvitamin D-1 alpha hydroxylase plays an important role in bone growth, calcium metabolism, and tissue differentiation. Previous studies have reported that mice deficient in 25-hydroxyvitamin D-1 alpha hydroxylase are affected by hypocalcemia, secondary hyperparathyroidism, retarded growth, and the skeletal abnormalities. In humans, defects in this enzyme causes pseudovitamin D deficiency rickets (vitamin D-dependent type 1A rickets), an autosomal recessive condition characterized by abnormal bone mineralization and impaired growth.

ALT Names :

25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial;25-OHD-1 alpha-hydroxylase;25-hydroxyvitamin D(3) 1-alpha-hydroxylase;VD3 1A hydroxylase;Calcidiol 1-monooxygenase;Cytochrome P450 subfamily XXVIIB polypeptide 1;Cytochrome P450C1 alpha;Cytochrome P450VD1-alpha;Cytochrome p450 27B1

Immunogen :

KLH-conjugated linear peptide corresponding to human CYP27B1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt