GABA Antibody | EMD Millipore ABN131 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

GABA Antibody

catalog :

ABN131

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Petromyzontiformes

application :

immunohistochemistry, enzyme immunoassay, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; Petromyzontiformes; 1:100; loading ...; fig 5a	Capantini L, von Twickel A, Robertson B, Grillner S. The pretectal connectome in lamprey. J Comp Neurol. 2017;525:753-772 pubmed publisher

product information

Catalog Number :

ABN131

Subcategory :

Neuroscience

Product Name :

Anti-GABA Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Host Name :

Rabbit

Antigen :

GABA

Conjugate :

Affinity Purified

Product Description :

Anti-GABA Antibody

Cross Reactivity :

Rat;All

Background :

Neurotransmitters can be defined as chemical substances that are released by the presynaptic neuron before being bound by receptors on the postsynaptic cell surface. It has been well established that the nervous system utilizes neurotransmitters for cell signaling. Neurotransmitters can be divided into two groups; low molecular weight transmitter molecules such as biogenic amines, purines, or amino acids, and bioactive peptides, of which more than 50 members have been identified in the mammalian central nervous system. Many low molecular weight neurotransmitters are produced within the axon terminal from common cellular metabolites and packaged into synaptic vesicles. The transport and delivery of vesicles containing neurotransmitter is a highly regulated and complex process. GABA (g-aminobutyric acid) is the major inhibitory neurotransmitter in the central nervous system that is involved in the pathogenesis of certain neurological and psychiatric disorders. GABA is produced from glutamic acid in a reaction catalyzed by glutamic acid decarboxylase. GABA interacts with the GABAA and GABAB receptors, which are widely distributed throughout the nervous system and in a variety of cell types. The immunolocalization, neuronal distribution, and vesicular compartmentalization of neurotransmitter molecules and their precursors are important for understanding the modulation, regulation, and function of neurotransmitters in the nervous system.

Immunogen :

BSA-conjugated GABA-Glutaraldehyde

Specificity :

This antibody is expected to demonstrate broad species reactivity.

Package Size :

100 μg

Uses :

Immunohistochemistry (Paraffin);Enzyme Immunoassay (ELISA)

Storage :

Stable for 1 year at 2-8°C from date of receipt