MDA5 Antibody | EMD Millipore ABF210 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MDA5 Antibody

catalog :

ABF210

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Chinese tree shrew, human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; Chinese tree shrew; fig s3b	Xu L, Yu D, Fan Y, Peng L, Wu Y, Yao Y. Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew. Proc Natl Acad Sci U S A. 2016;113:10950-5 pubmed publisher

product information

Catalog Number :

ABF210

Subcategory :

Cell Structure

Product Name :

Anti-MDA5 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9BYX4

Host Name :

Rabbit

Antigen :

MDA5

Conjugate :

Affinity Purified

Product Description :

Anti-MDA5 Antibody

Cross Reactivity :

Human

Background :

Melanoma differentiation-associated protein 5 (MDA5), also known as Interferon-induced helicase C domain-containing protein 1 (IFIH1) is a member of the helicase family (RLR subfamily). MDA5 plays an important role in recognizing various viral components and triggers antiviral responses. When stimulated by dsRNA, MDA5 recruits adaptor protein VISA causing the activation of IRF-3 and NF-κB. MDA5 is widely expressed at low levels with barely detectable levels found in , testis and lung. Mutations in MDA5 have been associated with diabetes mellitus insulin-dependent type 19.

ALT Names :

MDA5 Antibody;Melanoma differentiation-associated protein 5;Interferon-induced with helicase C domain protein 1;IFIH1

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human MDA5.

Specificity :

This antibody recognizes the C-terminus of MDA5.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry (Paraffin);Immunofluorescence

Storage :

Stable for 1 year at 2-8°C from date of receipt