Bst2 Antibody | EMD Millipore ABF200 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Bst2 Antibody

catalog :

ABF200

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

product information

Catalog Number :

ABF200

Subcategory :

Cell Structure

Product Name :

Anti-Bst2 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q8R2Q8

Host Name :

Rabbit

Antigen :

Bst2

Conjugate :

Affinity Purified

Product Description :

Anti-Bst2 Antibody

Cross Reactivity :

Human

Background :

Bone marrow stromal cell antigen 2 (BST-2, Bst2), also known as CD317, and HM1.24 antigen, is an IFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian viruses by directly tethering nascent virions to the membranes of infected cells. Bst2 has been shown to interact with various viruses, including: human immunodeficiency virus type 1 (HIV-1), mouse mammary tumor virus (MMTV) and murine leukemia virus (MLV), filoviridae: ebola virus (EBOV), arenaviridae: lassa virus (LASV), and rhabdoviridae: vesicular stomatitis virus (VSV). Bst2 may inhibit cell surface proteolytic activity of MMP14 causing decreased activation of MMP15 which results in inhibition of cell growth and migration. Additionally, it is implied to interact with LILRA4/ILT7, which results in providing negative feedback to the production of IFN by plasmacytoid dendritic cells in response to viral infection. This activity suggests that Bst2 can provide a potential therapeutic strategy for the treatment of HIV/AIDS. Bst2 may play a role in the organization of the subapical actin cytoskeleton in polarized epithelial cells

ALT Names :

Bone marrow stromal cell antigen 2;BST-2;CD317;HM1.24 antigen

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus of mouse Bst2.

Specificity :

This antibody recognizes the N-terminus of Bst2.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt