JMJD8 Antibody | EMD Millipore ABE91 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

JMJD8 Antibody

catalog :

ABE91

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, dog

application :

western blot

product information

Catalog Number :

ABE91

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-JMJD8 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q96S16

Host Name :

Rabbit

Antigen :

JMJD8

Conjugate :

Affinity Purified

Product Description :

Anti-JMJD8 Antibody

Cross Reactivity :

Human;Pig;Chimpanzee;Rhesus Macaque;Canine;Horse

Background :

Covalent modification of histones plays critical role in regulating chromatin structure and transcription. JMJD8 is one member of the family of JmjC domain-containing histone demethylation (JHDM) enzymes. These proteins remove specific methyl marks from histones. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed. While two isoforms of JMJD8 have been described, further study is still required to clarify the roles and mechanisms of JMJD8 among other JHDM protein family members.

ALT Names :

JMJD;JmjC domain-containing protein 8;Jumonji domain-containing protein 8

Immunogen :

KLH-conjugated linear peptide corresponding to human JMJD8.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt