FOXP3 Antibody, clone 3G3 | EMD Millipore ABE75 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

FOXP3 Antibody, clone 3G3

catalog :

ABE75

quantity :

100 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

3G3

reactivity :

human, mouse

application :

western blot, immunocytochemistry

product information

Catalog Number :

ABE75

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-FOXP3 Antibody, clone 3G3

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9BZS1

Host Name :

Rabbit

Antigen :

FOXP3

Conjugate :

Serum

Isotype :

IgG

Product Description :

Anti-FOXP3 Antibody, clone 3G3

Cross Reactivity :

Human;Mouse;Rat

Background :

FOXP3 (forkhead box P3) is a member of the FOX protein family and is thought to function as the master regulator in the development and function of regulatory T cells. As a member of the forkhead/winged-helix family of transcriptional regulators FOXP3 is believed to regulate expression through DNA binding. Mutations and deletions in the sequence encoding for FOXP3 expression lead to an inability to express FOXP3, causing an inability to regulate T cell development and leading to fatal autoimmune diseases such as IPEX and XLAAD. Conversely, other studies have shown high and wide expression of FOXP3 in several cancer cell lines and tumors, indicating that FOXP3 is involved in preventing immunity against malignant tumors.

ALT Names :

forkhead box P3;immune dysregulation, polyendocrinopathy, enteropathy, X-linked;immunodeficiency, polyendocrinopathy, enteropathy, X-linked

Immunogen :

Linear peptide corresponding to human FOXP3.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.