BAF180 Antibody | EMD Millipore ABE70 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

BAF180 Antibody

catalog :

ABE70

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:500; loading ...	Hopkins S, McGregor G, Murray J, Downs J, Savic V. Novel synthetic lethality screening method identifies TIP60-dependent radiation sensitivity in the absence of BAF180. DNA Repair (Amst). 2016;46:47-54 pubmed publisher
	Meisenberg C, Pinder S, Hopkins S, Wooller S, Benstead Hume G, Pearl F, et al. Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability. Mol Cell. 2019;73:212-223.e7 pubmed publisher

product information

Catalog Number :

ABE70

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-BAF180 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q86U86

Host Name :

Rabbit

Antigen :

BAF180

Conjugate :

Purified

Product Description :

Anti-BAF180 Antibody

Cross Reactivity :

Human;Rat;Mouse

Background :

BRG1-associated factor 180 (BAF180) is a subunit of the SWI/SNF-B (PBAF) chromatin remodeling complex, and is known to contain 6 bromo domains, 2 BAH domains, and a single HMG box DNA-binding domain. BAF180 has a critical and active role in the transcriptional activation and repression of specific genes via chromatin remodeling, including genes involved in the development of the heart, thus suggesting a role in mammalian development. Recent studies demonstrate BAF180 to suppress tumorigenesis through its ability to regulate both baseline and signal-dependent p21 transcription by its binding of the p21 promoter. Expression of BAF180 is reported in a wide range of tissues.

ALT Names :

polybromo 1;protein polybromo-1;BRG1-associated factor 180;polybromo-1D;Polybromo-1D

Immunogen :

GST-tagged recombinant protein corresponding to human BAF180.

Package Size :

100 µL

Uses :

Western Blotting;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt