N6-methyladenosine (m6A) Antibody | EMD Millipore ABE572 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

N6-methyladenosine (m6A) Antibody

catalog :

ABE572

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

chromatin immunoprecipitation

citations: 5

Reference
Su H, Wang G, Wu L, Ma X, Ying K, Zhang R. Transcriptome-wide map of m6A circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension. BMC Genomics. 2020;21:39 pubmed publisher
Baquero Perez B, Antanaviciute A, Yonchev I, Carr I, Wilson S, Whitehouse A. The Tudor SND1 protein is an m6A RNA reader essential for replication of Kaposi's sarcoma-associated herpesvirus. elife. 2019;8: pubmed publisher
Kuppers D, Arora S, Lim Y, Lim A, Carter L, Corrin P, et al. N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis. Nat Commun. 2019;10:4596 pubmed publisher
Miao W, Li L, Zhao Y, Dai X, Chen X, Wang Y. HSP90 inhibitors stimulate DNAJB4 protein expression through a mechanism involving N6-methyladenosine. Nat Commun. 2019;10:3613 pubmed publisher
Yadav P, Rajasekharan R. The m6A methyltransferase Ime4 epitranscriptionally regulates triacylglycerol metabolism and vacuolar morphology in haploid yeast cells. J Biol Chem. 2017;292:13727-13744 pubmed publisher

product information

Catalog Number :

ABE572

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-N6-methyladenosine (m6A) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Host Name :

Rabbit

Antigen :

N6-methyladenosine (m6A)

Conjugate :

Purified

Product Description :

Anti-N6-methyladenosine (m6A) Antibody

Cross Reactivity :

All

Background :

N6-methyladenosine (m6A), or methylation of the N6 position of adenosine is a posttranscriptional modification of RNA. Due to a lack of analytical methods, N6-methyladenosine is poorly understood, but new evidence suggests that it is a very common base modification and important physiological regulator. N6-methyladenosine is markedly increased throughout brain development, and is enriched near stop codons, microRNA-binding sites and UTRs, which indicates a fundamental role in the regulation of gene expression. N6-methyladenosine is also highly conserved between human and mouse.

ALT Names :

m6A

Immunogen :

BSA-conjugated N6-methyladenosine.

Package Size :

100 μg

Uses :

Dot Blot;Chromatin Immunoprecipitation (ChIP);RNA Binding Protein Immunoprecipitation (RIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt