CREB-1 Antibody | EMD Millipore ABE553 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

CREB-1 Antibody

catalog :

ABE553

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunocytochemistry, chromatin immunoprecipitation

product information

Catalog Number :

ABE553

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-CREB-1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P16220

Host Name :

Rabbit

Antigen :

CREB-1

Conjugate :

Affinity Purified

Product Description :

Anti-CREB-1 Antibody

Cross Reactivity :

Human;Rat

Background :

Cyclic AMP-responsive element-binding protein (CREB) is a beta ZIP transcription factor that activates target genes through cAMP response elements. CREB is able to mediate signals from numerous physiological stimuli, resulting in regulation of a broad array of cellular responses. While CREB is expressed in numerous tissues, it plays a large regulatory role in the nervous system. CREB is believed to play a key role in promoting neuronal survival, precursor proliferation, neurite outgrowth and neuronal differentiation in certain neuronal populations. Additionally, CREB signaling is involved in learning and memory in several organisms. CREB is able to selectively activate numerous downstream genes through interactions with different dimerization partners. CREB is activated by phosphorylation at Ser133 by various signaling pathways including Erk, Ca2+ and stress signaling. Some of the kinases involved in phosphorylating CREB at Ser133 are p90RSK, MSK, CaMKIV, and MAPKAPK-2.

ALT Names :

Cyclic AMP-responsive element-binding protein 1;CREB-1;cAMP-responsive element-binding protein 1

Immunogen :

KLH-conjugated linear peptide corresponding to the N-terminus of human CREB-1.

Specificity :

This antibody recognizes the N-terminus of CREB-1.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt