This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
c-Fos Antibody
catalog :
ABE457
quantity :
100 μg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 29
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3e
Su J, Li Z, Yamashita A, Kusumoto Yoshida I, Isomichi T, Hao L, et al. Involvement of the Nucleus Accumbens in Chocolate-induced Cataplexy. Sci Rep. 2020;10:4958 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:5000; loading ...; fig 1c
Calva C, Fayyaz H, Fadel J. Effects of Intranasal Orexin-A (Hypocretin-1) Administration on Neuronal Activation, Neurochemistry, and Attention in Aged Rats. Front Aging Neurosci. 2019;11:362 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:3000; loading ...; fig 5g
Zeng X, Ye M, Resch J, Jedrychowski M, Hu B, Lowell B, et al. Innervation of thermogenic adipose tissue via a calsyntenin 3β-S100b axis. Nature. 2019;569:229-235 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2f
Nagai J, Rajbhandari A, Gangwani M, Hachisuka A, Coppola G, Masmanidis S, et al. Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue. Cell. 2019;177:1280-1292.e20 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 5b
Lee S, Augustine V, Zhao Y, Ebisu H, Ho B, Kong D, et al. Chemosensory modulation of neural circuits for sodium appetite. Nature. 2019;568:93-97 pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:1000; loading ...; fig 1a
Li H, Pullmann D, Jhou T. Valence-encoding in the lateral habenula arises from the entopeduncular region. elife. 2019;8: pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig e4f, e7a
Huang T, Lin S, Malewicz N, Zhang Y, Zhang Y, Goulding M, et al. Identifying the pathways required for coping behaviours associated with sustained pain. Nature. 2019;565:86-90 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 5b
Mai H, Sharma N, Shin E, Nguyen B, Jeong J, Jang C, et al. Exposure to Far Infrared Ray Protects Methamphetamine-Induced Behavioral Sensitization in Glutathione Peroxidase-1 Knockout Mice via Attenuating Mitochondrial Burdens and Dopamine D1 Receptor Activation. Neurochem Res. 2018;43:1118-1135 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig s8f
Lagerlof O, Slocomb J, Hong I, Aponte Y, Blackshaw S, Hart G, et al. The nutrient sensor OGT in PVN neurons regulates feeding. Science. 2016;351:1293-6 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:10,000; loading ...; fig 2e
Anastasiadou S, Knöll B. The multiple sclerosis drug fingolimod (FTY720) stimulates neuronal gene expression, axonal growth and regeneration. Exp Neurol. 2016;279:243-260 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:5000; fig 4
Vincent K, Cornea V, Jong Y, Laferriere A, Kumar N, Mickeviciute A, et al. Intracellular mGluR5 plays a critical role in neuropathic pain. Nat Commun. 2016;7:10604 pubmed publisher
Hartley N, Gaulden A, Baldi R, Winters N, Salimando G, Rosas Vidal L, et al. Dynamic remodeling of a basolateral-to-central amygdala glutamatergic circuit across fear states. Nat Neurosci. 2019;22:2000-2012 pubmed publisher
Li H, Vento P, Parrilla Carrero J, Pullmann D, Chao Y, Eid M, et al. Three Rostromedial Tegmental Afferents Drive Triply Dissociable Aspects of Punishment Learning and Aversive Valence Encoding. Neuron. 2019;104:987-999.e4 pubmed publisher
Giannotti G, Heinsbroek J, Yue A, Deisseroth K, Peters J. Prefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval. Sci Rep. 2019;9:10709 pubmed publisher
Pan H, Fatima M, Li A, Lee H, Cai W, Horwitz L, et al. Identification of a Spinal Circuit for Mechanical and Persistent Spontaneous Itch. Neuron. 2019;103:1135-1149.e6 pubmed publisher
Pristerá A, Blomeley C, Lopes E, Threlfell S, Merlini E, Burdakov D, et al. Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration. Proc Natl Acad Sci U S A. 2019;116:3817-3826 pubmed publisher
Hupalo S, Martin A, Green R, Devilbiss D, Berridge C. Prefrontal Corticotropin-Releasing Factor (CRF) Neurons Act Locally to Modulate Frontostriatal Cognition and Circuit Function. J Neurosci. 2019;39:2080-2090 pubmed publisher
Matsui S, Sasaki T, Kohno D, Yaku K, Inutsuka A, Yokota Hashimoto H, et al. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice. Nat Commun. 2018;9:4604 pubmed publisher
Zhong L, Chen X, Park E, Sudhof T, Chen L. Retinoic Acid Receptor RARα-Dependent Synaptic Signaling Mediates Homeostatic Synaptic Plasticity at the Inhibitory Synapses of Mouse Visual Cortex. J Neurosci. 2018;38:10454-10466 pubmed publisher
Maynard K, Hobbs J, Phan B, Gupta A, Rajpurohit S, Williams C, et al. BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior. elife. 2018;7: pubmed publisher
Harris N, Isaac A, Gunther A, Merkel K, MELCHIOR J, Xu M, et al. Dorsal BNST α2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors. J Neurosci. 2018;38:8922-8942 pubmed publisher
Zhang Y, Liu S, Zhang Y, Goulding M, Wang Y, Ma Q. Timing Mechanisms Underlying Gate Control by Feedforward Inhibition. Neuron. 2018;99:941-955.e4 pubmed publisher
Wang Y, Cao L, Lee C, Matsuo T, Wu K, Asher G, et al. Large-scale forward genetics screening identifies Trpa1 as a chemosensor for predator odor-evoked innate fear behaviors. Nat Commun. 2018;9:2041 pubmed publisher
Galic S, Loh K, Murray Segal L, Steinberg G, Andrews Z, Kemp B. AMPK signaling to acetyl-CoA carboxylase is required for fasting- and cold-induced appetite but not thermogenesis. elife. 2018;7: pubmed publisher
Futatsuki T, Yamashita A, Ikbar K, Yamanaka A, Arita K, Kakihana Y, et al. Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia. Sci Rep. 2018;8:2717 pubmed publisher
Reppucci C, Gergely C, Veenema A. Activation patterns of vasopressinergic and oxytocinergic brain regions following social play exposure in juvenile male and female rats. J Neuroendocrinol. 2018;: pubmed publisher
Huang W, Chen Y, Page D. Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome. Nat Commun. 2016;7:13421 pubmed publisher
Scharner S, Prinz P, Goebel Stengel M, Kobelt P, Hofmann T, Rose M, et al. Activity-Based Anorexia Reduces Body Weight without Inducing a Separate Food Intake Microstructure or Activity Phenotype in Female Rats-Mediation via an Activation of Distinct Brain Nuclei. Front Neurosci. 2016;10:475 pubmed
Mangione A, Obara I, Maiarú M, Géranton S, Tassorelli C, Ferrari E, et al. Nonparalytic botulinum molecules for the control of pain. Pain. 2016;157:1045-55 pubmed publisher
product information
Catalog Number :
ABE457
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-c-Fos Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
P01100
Host Name :
Rabbit
Antigen :
c-Fos
Conjugate :
Affinity Purified
Product Description :
Anti-c-Fos Antibody
Cross Reactivity :
Human;Rat
Background :
c-Fos is a member of a family of immediate early gene (IEG) transcription factors (other members include Jun and Egr-1) also identified as proto-oncogenes. The basal expression of c-Fos and other IEGs is typically low but increases relatively quickly and often dramatically (15-30 min for mRNA; 30-60 min for protein) in response to changes in cellular activity typically caused by external stimuli, such as stress or neuronal activation. Thus, these IEGs are being used to indicate specific activity driven cellular activation including the identification of neurons activated by various growth factors, neuroactive drugs, and correlated changes in behavioral or physiological states.
ALT Names :
Proto-oncogene c-Fos;Cellular oncogene fos;G0/G1 switch regulatory protein 7
Immunogen :
KLH-conjugated linear peptide corresponding to the N-terminus of human c-Fos.
Specificity :
This antibody recognizes the N-terminus of c-Fos.
Package Size :
100 μg
Uses :
Western Blotting;Immunohistochemistry (Paraffin)
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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