trimethyl Histone H3 (Lys27) Antibody | EMD Millipore ABE44 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

trimethyl Histone H3 (Lys27) Antibody

catalog :

ABE44

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...; fig 3a western blot; mouse; loading ...; fig 3c	Yang L, Song L, Liu X, Bai L, Li G. KDM6A and KDM6B play contrasting roles in nuclear transfer embryos revealed by MERVL reporter system. EMBO Rep. 2018;19: pubmed publisher
	Harutyunyan A, Krug B, Chen H, Papillon Cavanagh S, Zeinieh M, De Jay N, et al. H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. Nat Commun. 2019;10:1262 pubmed publisher
	Kim J, Lee Y, Lu X, Song B, Fong K, Cao Q, et al. Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator. Cell Rep. 2018;25:2808-2820.e4 pubmed publisher
	Bogliotti Y, Wu J, Vilarino M, Okamura D, Soto D, Zhong C, et al. Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts. Proc Natl Acad Sci U S A. 2018;115:2090-2095 pubmed publisher
	Li H, Mai R, Huang H, Chou C, Chang Y, Chang Y, et al. DDX3 Represses Stemness by Epigenetically Modulating Tumor-suppressive miRNAs in Hepatocellular Carcinoma. Sci Rep. 2016;6:28637 pubmed publisher
	Mendoza Parra M, Saravaki V, Cholley P, Blum M, Billoré B, Gronemeyer H. Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification. F1000Res. 2016;5:54 pubmed publisher

product information

Catalog Number :

ABE44

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-trimethyl Histone H3 (Lys27) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q16695

Host Name :

Rabbit

Antigen :

trimethyl Histone H3 (Lys27)

Conjugate :

Affinity Purified

Product Description :

Anti-trimethyl Histone H3 (Lys27) Antibody

Cross Reactivity :

Human;Mouse

Background :

Histone H3 is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Histone H3 lysine 27 methylation (H3K27) is associated with heterochromatin formation and transcriptional repression.

ALT Names :

H3K27me3;Histone H3 (tri methyl K27);H3 histone family, member T;histone 3, H3;histone cluster 3, H3

Immunogen :

Branch peptide corresponding to human Histone H3 methylated at Lys27.

Specificity :

This antibody recognizes Histone H3 methylated at Lys27.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Peptide Inhibition Assay;Dot Blot

Storage :

Stable for 1 year at 2-8°C from date of receipt