β-Catenin Antibody | EMD Millipore ABE208 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

β-Catenin Antibody

catalog :

ABE208

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
western blot; rat; 1:20,000; loading ...; fig 1d	Liu Z, Sneve M, Haroldson T, Smith J, Drewes L. Regulation of Monocarboxylic Acid Transporter 1 Trafficking by the Canonical Wnt/Î²-Catenin Pathway in Rat Brain Endothelial Cells Requires Cross-talk with Notch Signaling. J Biol Chem. 2016;291:8059-69 pubmed publisher
	Baruah J, Hitzman R, Zhang J, Chaudhuri S, Mastej V, Wary K. The allosteric glycogen synthase kinase-3 inhibitor NP12 limits myocardial remodeling and promotes angiogenesis in an acute myocardial infarction model. J Biol Chem. 2017;292:20785-20798 pubmed publisher

product information

Catalog Number :

ABE208

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-β-Catenin Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P35222

Host Name :

Rabbit

Antigen :

β-Catenin

Conjugate :

Affinity Purified

Product Description :

Anti-β-Catenin Antibody

Cross Reactivity :

Human;Mouse;Rat;Horse;Ox

Background :

β-catenin is the founding member of the β -catenin family. This protein is comprised of 12 ARM repeats and is considered to have dual function depending on its localization. Cytoplasmic β -catenin is a critical component of E-cadherin/catening adhesion complexes and is involved in regulating cadherin-dependent cell-cell interactions.When localized to the nucleus, β -catenin serves a regulatory role by binding with transcription factors from the TCF/LEF family, activating transcription. Expression of β -catenin has been reported in a variety of hair follicle cells such as cells found in the inner and outer portions of the root sheaths, and the basal and peripheral matrix cells. It has also been observed in colon tissue. Defects in expression have been linked to the development of several tumors and cancers such as; colorectal cancer (CRC), medulloblastoma (MDB), ovarian cancer (OC), and pilomatrixoma (PTR).

ALT Names :

catenin (cadherin-associated protein), beta 1, 88kDa;catenin (cadherin-associated protein), beta 1 (88kD)

Immunogen :

KLH-conjugated linear peptide corresponding to the consensus GSK3 phosphorylation site of human β-Catenin.

Specificity :

Antibody recognizes β-Catenin at the N-terminus.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt