Nestin, Human Antibody | EMD Millipore ABD69 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nestin, Human Antibody

catalog :

ABD69

quantity :

50 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

African green monkey, human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:250; loading ...; fig 1s1a immunocytochemistry; African green monkey; 1:250; loading ...; fig 1s1a	Marchetto M, Hrvoj Mihic B, Kerman B, Yu D, Vadodaria K, Linker S, et al. Species-specific maturation profiles of human, chimpanzee and bonobo neural cells. elife. 2019;8: pubmed publisher
immunohistochemistry - paraffin section; human; 1:200; fig s3a	Zhang Y, Wang J, Huang W, Cai J, Ba J, Wang Y, et al. Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation. Nat Commun. 2018;9:3613 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 3f	Marigil M, Martinez Vélez N, Dominguez P, Idoate M, Xipell E, Patino Garcia A, et al. Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System. PLoS ONE. 2017;12:e0170501 pubmed publisher
immunohistochemistry - frozen section; human; 1:200; fig 1c immunocytochemistry; human; 1:200; fig s4a	Lee I, Koo K, Jung K, Kim M, Kim I, Hwang K, et al. Neurogenin-2-transduced human neural progenitor cells attenuate neonatal hypoxic-ischemic brain injury. Transl Res. 2017;183:121-136.e9 pubmed publisher
	D Aiuto L, Bloom D, Naciri J, Smith A, Edwards T, McClain L, et al. Modeling Herpes Simplex Virus 1 Infections in Human Central Nervous System Neuronal Cells Using Two- and Three-Dimensional Cultures Derived from Induced Pluripotent Stem Cells. J Virol. 2019;93: pubmed publisher
	Tousley A, Iuliano M, Weisman E, Sapp E, Zhang N, Vodicka P, et al. Rac1 Activity Is Modulated by Huntingtin and Dysregulated in Models of Huntington's Disease. J Huntingtons Dis. 2019;8:53-69 pubmed publisher
	Beldick S, Hong J, Altamentova S, Khazaei M, Hundal A, Zavvarian M, et al. Severe-combined immunodeficient rats can be used to generate a model of perinatal hypoxic-ischemic brain injury to facilitate studies of engrafted human neural stem cells. PLoS ONE. 2018;13:e0208105 pubmed publisher
	Rostami J, Holmqvist S, Lindström V, Sigvardson J, Westermark G, Ingelsson M, et al. Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes. J Neurosci. 2017;37:11835-11853 pubmed publisher
	Beretta S, Cunningham K, Haus D, Gold E, Perez H, López Velázquez L, et al. Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury. Cell Transplant. 2017;26:1247-1261 pubmed publisher

product information

Catalog Number :

ABD69

Subcategory :

Stem Cell Research

Product Name :

Anti-Nestin, Human Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P48681

Host Name :

Rabbit

Antigen :

Nestin

Conjugate :

Serum

Product Description :

Anti-Nestin, Human Antibody

Cross Reactivity :

Human

Background :

Nestin, a large intermediate filament protein (class Type VI) expressed during development and in myotendinous and neuromuscular junctions. Nestin expression is restricted, typically disappearing by E18. Nestin is thought to be a reasonable neuronal marker; however, recent studies have found nestin expression in other cell types such as endothelial cells {Folia Biologica, 44(5):155, 1998}. Nestin identifies the most primitive neuroepithelium but also identifies many other embryonic tissues, so it is not specific for CNS. Nestin expression is seen in almost all GBMs (Glioblastoma mulitformes) and many melanomas (both primary and metastatic) but not in any metastatic carcinoma.

ALT Names :

Nestin

Immunogen :

GST-tagged recombinant protein corresponding to human Nestin.

Specificity :

This antibody recognizes human Nestin. Antibody is not reactive with rat and mouse Nestin protein.

Package Size :

50 µL

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt.