Mitofusin-1 Antibody | EMD Millipore ABC41 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Mitofusin-1 Antibody

catalog :

ABC41

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, flow cytometry

citations: 2

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 1:1500; loading ...; fig 4e western blot; human; 1:1500; loading ...; fig 3g	Menges S, Minakaki G, Schaefer P, Meixner H, Prots I, Schlötzer Schrehardt U, et al. Alpha-synuclein prevents the formation of spherical mitochondria and apoptosis under oxidative stress. Sci Rep. 2017;7:42942 pubmed publisher
western blot; mouse	Hagl S, Berressem D, Grewal R, Sus N, Frank J, Eckert G. Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci. 2016;19:1-10 pubmed publisher

product information

Catalog Number :

ABC41

Subcategory :

Cell Structure

Product Name :

Anti-Mitofusin-1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q8IWA4

Host Name :

Rabbit

Antigen :

Mitofusin-1

Conjugate :

Affinity Purified

Product Description :

Anti-Mitofusin-1 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

Along with Mitofusin-2 (Mfn2), Mitofusin-1 (Mfn1) is a known protein mediator of mitochondrial fusion. Mitochondrial fusion regulates mitochondrial morphogensis and supports complementation between mitochondrial genomes in mammalian cells. Two Mfn1 transcripts are detected at similar levels in a variety of human tissues and are dramatically elevated in the heart. Human Mfn1 is known to be localized in the mitochondria. It is reported that point mutations in the conserved G1 and G2 region of the Mfn1 GTPase domain result in decreased formation and fragmentation of the mitochondria, respectively.

ALT Names :

Fzo homolog;Transmembrane GTPase MFN1, Mitofusion-1

Immunogen :

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Mitofusin-1.

Specificity :

This antibody recognizes Mitofusin-1 at the cytoplasmic domain.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt