phospho ULK1 Antibody (Thr574) | EMD Millipore ABC212 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho ULK1 Antibody (Thr574)

catalog :

ABC212

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 3c	Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-Î²-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher

product information

Catalog Number :

ABC212

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-phospho ULK1 Antibody (Thr574)

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O70405

Host Name :

Rabbit

Antigen :

phospho ULK1 (Thr574)

Conjugate :

Affinity Purified

Product Description :

Anti-phospho ULK1 Antibody (Thr574)

Cross Reactivity :

Human

Background :

ULK1 or autophagy-related protein 1 homolog (ATG1) is a serine/threonine protein kinase. It is a ubiquitously expressed protein that is highly abundant in the brain, skeletal muscle, and heart. It is involved in the signaling pathway of mTOR receptors leading to the regulation of autophagy in nutrient-deprived cells. mTOR may interact with ULK1 as a complex of ULK1/FIP200/Atg13. ULK1 may play an important role in neuronal development: Elimination of ULK1's enzymatic activity by targeted disruption of its kinase domain has blocked the outgrowth of neurons in the developing mouse brain, possibly by blocking the ULK1-mediated trafficking of neurotrophins.

ALT Names :

Serine/threonine-protein kinase ULK1;Serine/threonine-protein kinase Unc51.1;Unc-51-like kinase 1

Immunogen :

KLH-conjugated linear peptide corresponding to mouse ULK1 phosphorylated at Thr574.

Package Size :

100 μg

Uses :

Western Blotting;Peptide Inhibition Assay

Storage :

Stable for 1 year at 2-8°C from date of receipt