phospho-ULK1 (Ser555) Antibody | EMD Millipore ABC124 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho-ULK1 (Ser555) Antibody

catalog :

ABC124

quantity :

100 μg

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human, mouse, cow

application :

western blot

citations: 1

Reference
Lam W, Jiang Z, Guan F, Huang X, Hu R, Wang J, et al. PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment. Sci Rep. 2015;5:9384 pubmed publisher

product information

Catalog Number :

ABC124

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-phospho-ULK1 (Ser555) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O75385

Host Name :

Rabbit

Antigen :

phospho-ULK1 (Ser555)

Conjugate :

Affinity Purified

Product Description :

Anti-phospho-ULK1 (Ser555) Antibody

Cross Reactivity :

Human;Mouse;Rat;Bovine;Xenopus

Background :

ULK1 or autophagy-related protein 1 homolog (ATG1) is a serine/threonine protein kinase. It is a ubiquitously expressed protein that is highly abundant in the brain, skeletal muscle, and heart. It is involved in the signaling pathway of mTOR receptors leading to the regulation of autophagy in nutrient-deprived cells. mTOR may interact with ULK1 as a complex of ULK1/FIP200/Atg13. ULK1 may play an important role in neuronal development: Elimination of ULK1's enzymatic activity by targeted disruption of its kinase domain has blocked the outgrowth of neurons in the developing mouse brain, possibly by blocking the ULK1-mediated trafficking of neurotrophins.

ALT Names :

Serine/threonine-protein kinase ULK1;Autophagy-related protein 1 homolog;ATG1;hATG1;Unc-51-like kinase 1

Immunogen :

KLH-conjugated linear peptide corresponding to human ULK1 phosphorylated at Ser555.

Specificity :

This antibody recognizes ULK1 phosphorylated at Ser555.

Package Size :

100 μg

Uses :

Western Blotting;Peptide Inhibition Assay

Storage :

Stable for 1 year at 2-8°C from date of receipt