14-3-3 ζ Antibody | EMD Millipore AB9746 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

14-3-3 ζ Antibody

catalog :

AB9746

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, chicken, bovine

application :

western blot, ELISA, immunohistochemistry

product information

Catalog Number :

AB9746

Subcategory :

Neuroscience

Product Name :

Anti-14-3-3 ζ Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P63104

Host Name :

Rabbit

Antigen :

14-3-3 ζ

Conjugate :

Serum

Product Description :

Anti-14-3-3 ζ Antibody

Cross Reactivity :

Bovine;Chicken;Human;Mouse;Rat;Rabbit;Sheep

Background :

Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimmers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders: for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer's. The 14-3-3 zeta antibody is one of a panel of antibodies that were generated against 14-3-3 isoforms and have demonstrated their potential for use as an ELISA-based diagnostic tool. These antibodies will allow the research to investigate the role of this protein in key cellular processes and neurological disorders such as Creutzfeldt-Jakob, Alzheimer's and Parkinson's Disease.

Immunogen :

Synthetic peptide from the N-terminal area of sheep 14-3-3 zeta.

Specificity :

14-3-3 zeta. By Western blot the antibody recognizes the ~30 kDa protein.

Package Size :

100 µL

Uses :

ELISA;Western Blotting;Immunohistochemistry

Storage :

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.