Neuron Specific Enolase Antibody | EMD Millipore AB951 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Neuron Specific Enolase Antibody

catalog :

AB951

quantity :

500 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:60,000; fig 1 western blot; human; 1:60,000; fig 1	Tiwari S, Mizuno K, Ghosh A, Aziz W, Troakes C, Daoud J, et al. Alzheimer-related decrease in CYFIP2 links amyloid production to tau hyperphosphorylation and memory loss. Brain. 2016;139:2751-2765 pubmed
	Winchenbach J, Düking T, Berghoff S, Stumpf S, Hülsmann S, Nave K, et al. Inducible targeting of CNS astrocytes in Aldh1l1-CreERT2 BAC transgenic mice. F1000Res. 2016;5:2934 pubmed publisher
	Ramos Rodriguez J, Infante Garcia C, Galindo Gonzalez L, Garcia Molina Y, Lechuga Sancho A, Garcia Alloza M. Increased Spontaneous Central Bleeding and Cognition Impairment in APP/PS1 Mice with Poorly Controlled Diabetes Mellitus. Mol Neurobiol. 2016;53:2685-97 pubmed publisher

product information

Catalog Number :

AB951

Subcategory :

Neuroscience

Product Name :

Anti-Neuron Specific Enolase Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P09104

Host Name :

Rabbit

Antigen :

Neuron Specific Enolase

Conjugate :

Serum

Product Description :

Anti-Neuron Specific Enolase Antibody

Cross Reactivity :

Bovine;Rat

Background :

The glycolytic enzyme enolase (2-phospho-D-glycerate hydrolase, E.C. 4.2.1.11) is composed of two subunits and exists in three molecular forms in human brain: non-neuronal enolase (NNE; alpha, alpha'-enolase), neuron-specific enolase (NSE; gamma,gamma'-enolase, also known as 14-3-2 protein and NSP)(Grasso et al. 1977; Schmechel et al. 1979) and the short-lived heterodimer alpha, gamma'-enolase. The neuron specific form is a highly acidic homodimeric protin of 78kDa (Schmechel et al. 1978), which has been found in central and peripheral nervous elements and also in many neuroendocrine cells and derivative tumors (Marangos 1985). NSE is regarded as the best described serum marker for small cell lung cancer. In addition, the measurement of NSE levels in both serum and cerebrospinal fluid following cerebral ischaemia and traumatic head injury provides a reliable laboratory indicator of the degree of brain cell damage and may allow early prediction of prognostic outcome (DeGiorgio et al. 1995; Yamazaki et al. 1995).

ALT Names :

NSE; gamma Enolase; Neural Enolase; Enolase 2

Immunogen :

Synthetic peptide obtained from hNSE.

Specificity :

AB951 stains many neuronal cell bodies and processes within the central and peripheral nervous system.

Package Size :

500 μL

Uses :

Immunohistochemistry;Immunohistochemistry (Paraffin);Western Blotting

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.