This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Apolipoprotein E Antibody
catalog :
AB947
quantity :
1 mL
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - frozen section
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; 1:400; loading ...; fig s8b
Plemel J, Stratton J, Michaels N, Rawji K, Zhang E, Sinha S, et al. Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion. Sci Adv. 2020;6:eaay6324 pubmed publisher
  • immunoprecipitation; mouse; loading ...; fig 4a
  • western blot; mouse; 1:2000; loading ...; fig 3b
Oh S, Kim J, Park S, Lee J. Associative Interactions among Zinc, Apolipoprotein E, and Amyloid-β in the Amyloid Pathology. Int J Mol Sci. 2020;21: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 4h
Reichenbach N, Delekate A, Plescher M, Schmitt F, Krauss S, Blank N, et al. Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model. EMBO Mol Med. 2019;11: pubmed publisher
  • western blot; human; 1:2000; fig 5A
Fan J, Zareyan S, Zhao W, Shimizu Y, Pfeifer T, Tak J, et al. Identification of a Chrysanthemic Ester as an Apolipoprotein E Inducer in Astrocytes. PLoS ONE. 2016;11:e0162384 pubmed publisher
Zhang Q, Presswalla F, Calton M, Charniga C, Stern J, Temple S, et al. Highly Differentiated Human Fetal RPE Cultures Are Resistant to the Accumulation and Toxicity of Lipofuscin-Like Material. Invest Ophthalmol Vis Sci. 2019;60:3468-3479 pubmed publisher
Muth C, Hartmann A, Sepulveda Falla D, Glatzel M, Krasemann S. Phagocytosis of Apoptotic Cells Is Specifically Upregulated in ApoE4 Expressing Microglia in vitro. Front Cell Neurosci. 2019;13:181 pubmed publisher
Götzl J, Brendel M, Werner G, Parhizkar S, Sebastian Monasor L, Kleinberger G, et al. Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. EMBO Mol Med. 2019;: pubmed publisher
Lessard C, Malnik S, Zhou Y, Ladd T, Cruz P, Ran Y, et al. High-affinity interactions and signal transduction between Aβ oligomers and TREM2. EMBO Mol Med. 2018;10: pubmed publisher
Tay T, Sagar -, Dautzenberg J, Grün D, Prinz M. Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration. Acta Neuropathol Commun. 2018;6:87 pubmed publisher
Tensaouti Y, Stephanz E, Yu T, Kernie S. ApoE Regulates the Development of Adult Newborn Hippocampal Neurons. Eneuro. 2018;5: pubmed publisher
Kara E, Marks J, Roe A, Commins C, Fan Z, Calvo Rodríguez M, et al. A flow cytometry-based in vitro assay reveals that formation of apolipoprotein E (ApoE)-amyloid beta complexes depends on ApoE isoform and cell type. J Biol Chem. 2018;293:13247-13256 pubmed publisher
Kara E, Marks J, Fan Z, Klickstein J, Roe A, Krogh K, et al. Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay. J Biol Chem. 2017;292:14720-14729 pubmed publisher
Pilgrim M, Lengyel I, Lanzirotti A, Newville M, Fearn S, Emri E, et al. Subretinal Pigment Epithelial Deposition of Drusen Components Including Hydroxyapatite in a Primary Cell Culture Model. Invest Ophthalmol Vis Sci. 2017;58:708-719 pubmed publisher
Saini J, Corneo B, Miller J, Kiehl T, Wang Q, Boles N, et al. Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration. Cell Stem Cell. 2017;20:635-647.e7 pubmed publisher
product information
Catalog Number :
AB947
Subcategory :
Metabolism
Product Name :
Anti-Apolipoprotein E Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
P02649
Host Name :
Goat
Antigen :
Apolipoprotein E
Conjugate :
Serum
Product Description :
Anti-Apolipoprotein E Antibody
Cross Reactivity :
Human;Primate
ALT Names :
ApoE
Immunogen :
Recombinant human apolipoprotein E.
Specificity :
Monospecific for Apolipoprotein E by immunoelectrophoresis when tested against pooled human plasma and twice concentrated pooled human serum. Reacts with Apo E isoforms E2, E3 and E4 by Western blot.
Package Size :
1 mL
Uses :
Immunohistochemistry;Western Blotting
Storage :
Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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