Mouse Collagen Type I Antibody | EMD Millipore AB765P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Mouse Collagen Type I Antibody

catalog :

AB765P

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; loading ...; fig 7a	Bozic M, Caus M, Rodrigues Díez R, Pedraza N, Ruiz Ortega M, Garí E, et al. Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis. Nat Commun. 2020;11:1943 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...	Luxan G, Stewen J, Díaz N, Kato K, Maney S, Aravamudhan A, et al. Endothelial EphB4 maintains vascular integrity and transport function in adult heart. elife. 2019;8: pubmed publisher
immunohistochemistry; human; 1:200; loading ...; fig 2s1c	Bayer S, Grither W, Brenot A, Hwang P, Barcus C, Ernst M, et al. DDR2 controls breast tumor stiffness and metastasis by regulating integrin mediated mechanotransduction in CAFs. elife. 2019;8: pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:100–1:250	Rickelt S, Hynes R. Antibodies and methods for immunohistochemistry of extracellular matrix proteins. Matrix Biol. 2018;71-72:10-27 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 9a	Saxon J, Baer D, Barton J, Hawkins T, Wu B, Trusk T, et al. BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Dev Biol. 2017;430:113-128 pubmed publisher
western blot; human; 1:1000; fig s7a	Olivares O, Mayers J, Gouirand V, Torrence M, Gicquel T, Borge L, et al. Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions. Nat Commun. 2017;8:16031 pubmed publisher
western blot; mouse; loading ...; fig 1b	Gocheva V, Naba A, Bhutkar A, Guardia T, Miller K, Li C, et al. Quantitative proteomics identify Tenascin-C as a promoter of lung cancer progression and contributor to a signature prognostic of patient survival. Proc Natl Acad Sci U S A. 2017;114:E5625-E5634 pubmed publisher
immunohistochemistry - frozen section; mouse; fig s3b immunocytochemistry; mouse; loading ...; fig s4a	McKee K, Crosson S, Meinen S, Reinhard J, Ruegg M, Yurchenco P. Chimeric protein repair of laminin polymerization ameliorates muscular dystrophy phenotype. J Clin Invest. 2017;127:1075-1089 pubmed publisher
western blot; mouse; loading ...; fig 3c	Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C. Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep. 2017;7:42725 pubmed publisher
immunocytochemistry; mouse; loading ...; fig 5c	Ishikawa Y, Ito S, Nagata K, Sakai L, Bachinger H. Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules. Proc Natl Acad Sci U S A. 2016;113:E6036-E6044 pubmed
immunohistochemistry - paraffin section; mouse; 1:100; tbl 1 western blot; mouse; 1:1000; tbl 2	Muñoz Félix J, Pérez Roque L, Núñez Gómez E, Oujo B, Arevalo M, Ruiz Remolina L, et al. Overexpression of the short endoglin isoform reduces renal fibrosis and inflammation after unilateral ureteral obstruction. Biochim Biophys Acta. 2016;1862:1801-14 pubmed publisher
immunocytochemistry; mouse; 1:500; fig 12	Ufimtseva E. Differences between Mycobacterium-Host Cell Relationships in Latent Tuberculous Infection of Mice Ex Vivo and Mycobacterial Infection of Mouse Cells In Vitro. J Immunol Res. 2016;2016:4325646 pubmed publisher
	Omari S, Makareeva E, Roberts Pilgrim A, Mirigian L, Jarnik M, Ott C, et al. Noncanonical autophagy at ER exit sites regulates procollagen turnover. Proc Natl Acad Sci U S A. 2018;115:E10099-E10108 pubmed publisher
	Rayagiri S, Ranaldi D, Raven A, Mohamad Azhar N, Lefebvre O, Zammit P, et al. Basal lamina remodeling at the skeletal muscle stem cell niche mediates stem cell self-renewal. Nat Commun. 2018;9:1075 pubmed publisher
	Ito S, Ogawa K, Takeuchi K, Takagi M, Yoshida M, Hirokawa T, et al. A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis. J Biol Chem. 2017;292:20076-20085 pubmed publisher

product information

Catalog Number :

AB765P

Subcategory :

Cell Structure

Product Name :

Anti-Mouse Collagen Type I Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P02452

Host Name :

Rabbit

Antigen :

Mouse Collagen Type I

Conjugate :

Purified

Isotype :

IgG

Product Description :

Anti-Mouse Collagen Type I Antibody

Cross Reactivity :

Mouse

Background :

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content. It is one of the long, fibrous structural proteins whose functions are quite different from those of globular proteins such as enzymes; tough bundles of collagen called collagen fibers are a major component of the extracellular matrix that supports most tissues and gives cells structure from the outside, but collagen is also found inside certain cells. Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and teeth. Along with soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging. It strengthens blood vessels and plays a role in tissue development. It is present in the cornea and lens of the eye in crystalline form. Collagen occurs in many places throughout the body. There are 12 types of collagen described in literature. Collagen Type 1: This is the most abundant collagen of the human body. It is present in scar tissue, the end product when tissue heals by repair. It is found in tendons, the endomysium of myofibrils and the organic part of bone. Collagen Type 4: It is present in basal lamina and the eye lens. Also serves as part of the filtration system in capillaries and the glomeruli of nephron in the kidney.

Immunogen :

Collagen Type I extracted and purified from mouse skin.

Specificity :

Recognizes mouse Collagen Type I.

Package Size :

100 μg

Uses :

ELISA;Immunohistochemistry;Radioimmunoassay;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.