Collagen Antibody, Type IV | EMD Millipore AB756P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Collagen Antibody, Type IV

catalog :

AB756P

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

immunohistochemistry, immunocytochemistry, radioimmunoassay, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 17

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 1g	Kjell J, Fischer Sternjak J, Thompson A, Friess C, Sticco M, Salinas F, et al. Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis. Cell Stem Cell. 2020;26:277-293.e8 pubmed publisher
immunohistochemistry - paraffin section; mouse; loading ...	Muraoka H, Hasegawa K, Sakamaki Y, Minakuchi H, Kawaguchi T, Yasuda I, et al. Role of Nampt-Sirt6 Axis in Renal Proximal Tubules in Extracellular Matrix Deposition in Diabetic Nephropathy. Cell Rep. 2019;27:199-212.e5 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 2f	Naito H, Iba T, Wakabayashi T, Tai Nagara I, Suehiro J, Jia W, et al. TAK1 Prevents Endothelial Apoptosis and Maintains Vascular Integrity. Dev Cell. 2019;48:151-166.e7 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 2d	Abeln M, Albers I, Peters Bernard U, Flächsig Schulz K, Kats E, Kispert A, et al. Sialic acid is a critical fetal defense against maternal complement attack. J Clin Invest. 2019;129:422-436 pubmed publisher
immunohistochemistry - frozen section; mouse; fig s1d	Yu Q, Song W, Wang D, Zeng Y. Identification of blood vascular endothelial stem cells by the expression of protein C receptor. Cell Res. 2016;26:1079-1098 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; fig 6	Greulich F, Rudat C, Farin H, Christoffels V, Kispert A. Lack of Genetic Interaction between Tbx18 and Tbx2/Tbx20 in Mouse Epicardial Development. PLoS ONE. 2016;11:e0156787 pubmed publisher
immunohistochemistry; mouse; fig 3	Trembley M, Velasquez L, Small E. Epicardial Outgrowth Culture Assay and Ex Vivo Assessment of Epicardial-derived Cell Migration. J Vis Exp. 2016;: pubmed publisher
immunohistochemistry - paraffin section; mouse; fig s1a	Pietilä I, Prunskaite Hyyryläinen R, Kaisto S, Tika E, van Eerde A, Salo A, et al. Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS ONE. 2016;11:e0147171 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:200; fig 4	Allaire J, Roy S, Ouellet C, Lemieux Ã, Jones C, Paquet M, et al. Bmp signaling in colonic mesenchyme regulates stromal microenvironment and protects from polyposis initiation. Int J Cancer. 2016;138:2700-12 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s4a	Leiva M, Quintana J, Ligos J, Hidalgo A. Haematopoietic ESL-1 enables stem cell proliferation in the bone marrow by limiting TGFβ availability. Nat Commun. 2016;7:10222 pubmed publisher
	Zaitoun I, Cikla U, Zafer D, Udho E, Almomani R, Suscha A, et al. Attenuation of Retinal Vascular Development in Neonatal Mice Subjected to Hypoxic-Ischemic Encephalopathy. Sci Rep. 2018;8:9166 pubmed publisher
	Moll S, Yasui Y, Abed A, Murata T, Shimada H, Maeda A, et al. Selective pharmacological inhibition of DDR1 prevents experimentally-induced glomerulonephritis in prevention and therapeutic regime. J Transl Med. 2018;16:148 pubmed publisher
	Crist A, Lee A, Patel N, Westhoff D, Meadows S. Vascular deficiency of Smad4 causes arteriovenous malformations: a mouse model of Hereditary Hemorrhagic Telangiectasia. Angiogenesis. 2018;21:363-380 pubmed publisher
	Di Russo J, Luik A, Yousif L, Budny S, Oberleithner H, Hofschröer V, et al. Endothelial basement membrane laminin 511 is essential for shear stress response. EMBO J. 2017;36:183-201 pubmed publisher
	Lucitti J, Tarte N, Faber J. Chloride intracellular channel 4 is required for maturation of the cerebral collateral circulation. Am J Physiol Heart Circ Physiol. 2015;309:H1141-50 pubmed publisher
	Anderson C, Thorsteinsdóttir S, Borycki A. Sonic hedgehog-dependent synthesis of laminin alpha1 controls basement membrane assembly in the myotome. Development. 2009;136:3495-504 pubmed publisher
	Li X, Chen Y, Scheele S, Arman E, Haffner Krausz R, Ekblom P, et al. Fibroblast growth factor signaling and basement membrane assembly are connected during epithelial morphogenesis of the embryoid body. J Cell Biol. 2001;153:811-22 pubmed

product information

Catalog Number :

AB756P

Subcategory :

Cell Structure

Product Name :

Anti-Collagen Antibody, Type IV

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P53420

Host Name :

Rabbit

Antigen :

Collagen

Conjugate :

Purified

Product Description :

Anti-Collagen Antibody, Type IV

Cross Reactivity :

Mouse

Background :

Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content. It is one of the long, fibrous structural proteins whose functions are quite different from those of globular proteins such as enzymes; tough bundles of collagen called collagen fibers are a major component of the extracellular matrix that supports most tissues and gives cells structure from the outside, but collagen is also found inside certain cells. Collagen has great tensile strength, and is the main component of fascia, cartilage, ligaments, tendons, bone and teeth. Along with soft keratin, it is responsible for skin strength and elasticity, and its degradation leads to wrinkles that accompany aging. It strengthens blood vessels and plays a role in tissue development. It is present in the cornea and lens of the eye in crystalline form. Collagen occurs in many places throughout the body. There are 12 types of collagen described in literature. Collagen Type 1: This is the most abundant collagen of the human body. It is present in scar tissue, the end product when tissue heals by repair. It is found in tendons, the endomysium of myofibrils and the organic part of bone. Collagen Type 4: It is present in basal lamina and the eye lens. Also serves as part of the filtration system in capillaries and the glomeruli of nephron in the kidney.

Immunogen :

Collagen Type IV extracted and purified from mouse tumor tissues.

Specificity :

Antibody shows less than 0.1% reactivity with human Collagen types IV, V and mouse Collagen Types I, II, III, mouse Fibronectin, and mouse laminin.

Package Size :

100 μg

Uses :

ELISA;Immunofluorescence;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at -20ºC from date of receipt.