EB1 Antibody | EMD Millipore AB6057 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

EB1 Antibody

catalog :

AB6057

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1d	Lee I, Kim G, Bae J, Kim J, Rhee K, Hwang D. The DNA replication protein Cdc6 inhibits the microtubule-organizing activity of the centrosome. J Biol Chem. 2017;292:16267-16276 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500; loading ...; fig 5b	Benbow S, Wozniak K, Kulesh B, Savage A, Slusher B, Littlefield B, et al. Microtubule-Targeting Agents Eribulin and Paclitaxel Differentially Affect Neuronal Cell Bodies in Chemotherapy-Induced Peripheral Neuropathy. Neurotox Res. 2017;32:151-162 pubmed publisher
immunohistochemistry; mouse; 1:500; fig 5b	Benbow S, Cook B, Reifert J, Wozniak K, Slusher B, Littlefield B, et al. Effects of Paclitaxel and Eribulin in Mouse Sciatic Nerve: A Microtubule-Based Rationale for the Differential Induction of Chemotherapy-Induced Peripheral Neuropathy. Neurotox Res. 2016;29:299-313 pubmed publisher

product information

Catalog Number :

AB6057

Subcategory :

Cell Structure

Product Name :

Anti-EB1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q15691

Host Name :

Rabbit

Antigen :

EB1

Conjugate :

Purified

Product Description :

Anti-EB1 Antibody

Cross Reactivity :

Human;Mouse;Rat

Background :

End binding protein 1 (EB1) is thought to be associated with adenomatous polyposis coli (APC) and may play a part in regulation of microtubule dynamics in the mammalian cells. EB1 could also play a role in the regulation of microtubule assembly and stability. EB1 is essential for proper cilia assembly in fibroblasts. EB1 has been shown to excite spontaneous nucleation and microtubule growth. APC gene mutation and the loss of negatively regulating WNT signaling is thought to play a role in the proliferation changes of cancer. The loss of association with EB1 could contribute to the development of certain cancers.

ALT Names :

microtubule-associated protein, RP/EB family, member 1;adenomatous polyposis coli-binding protein EB1;microtubule-associated protein RP/EB family member 1;End-binding protein 1;APC-binding protein EB1

Immunogen :

KLH-conjugated linear peptide corresponding to the C-terminus of human EB1.

Specificity :

This antibody recognizes EB1 at the C-terminus. EB1 is 67% homologous to EB3.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt