MMP-1 Antibody, hinge region | EMD Millipore AB6002 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MMP-1 Antibody, hinge region

catalog :

AB6002

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 3

Reference
He R, Kidder B. Culture of haploid blastocysts in FGF4 favors the derivation of epiblast stem cells with a primed epigenetic and transcriptional landscape. Sci Rep. 2018;8:10775 pubmed publisher
Wang F, McCannell K, Boskovic A, Zhu X, Shin J, Yu J, et al. Rlim-Dependent and -Independent Pathways for X Chromosome Inactivation in Female ESCs. Cell Rep. 2017;21:3691-3699 pubmed publisher
Carnesecchi J, Forcet C, Zhang L, Tribollet V, Barenton B, Boudra R, et al. ERR? induces H3K9 demethylation by LSD1 to promote cell invasion. Proc Natl Acad Sci U S A. 2017;114:3909-3914 pubmed publisher

product information

Catalog Number :

AB6002

Subcategory :

Cell Structure

Product Name :

Anti-MMP-1 Antibody, hinge region

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P03956

Host Name :

Rabbit

Antigen :

MMP-1

Conjugate :

Affinity Purified

Product Description :

Anti-MMP-1 Antibody, hinge region

Cross Reactivity :

Human;Human

Background :

All cells within tissues are surrounded by an extracellular matrix (ECM) giving the tissues shape and structure. The ECM is constantly being remodeled and constant communication is maintained between cells through this matrix. Secreted proteins, termed matrix metalloproteinases (MMPs), are involved in the modulation of cell matrix interactions. MMPs are Zn2+ binding endopeptidases that degrade various components of the ECM. MMPs are enzymes implicated in normal and pathologic tissue remodeling processes, wound healing, angiogenesis, and tumor invasion. These enzymes are very potent when active, and are associated with extracellular space inhibitors called TIMPs (tissue inhibitors of matrix metalloproteinases). MMP1, also known as interstitial collagenase, is the only enzyme able to initiate the breakdown of the interstitial collagens, types I, II, and III.

ALT Names :

Fibroblast collagenase;Matrix metalloproteinase-1;matrix metallopeptidase 1;interstitial collagenase;matrix metalloprotease 1

Immunogen :

KLH-conjugated synthetic peptide corresponding to the hinge region of human MMP-1.

Specificity :

The antibody recognizes an internal domain of human MMP-1 containing the hinge region. It does not cross react with MMP-2, MMP-9, or MMP-13.

Package Size :

100 μg

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt