product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Glial Fibrillary Acidic Protein (GFAP) Antibody
catalog :
AB5804
quantity :
50 µL
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
African green monkey, human, mouse, rat, dogs, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 40
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:500; loading ...; fig 4s3a
Farhy C, Hariharan S, Ylanko J, Orozco L, Zeng F, Pass I, et al. Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; African green monkey; 1:12500; loading ...; fig 3a
Munger E, Edler M, Hopkins W, Ely J, Erwin J, Perl D, et al. Astrocytic changes with aging and Alzheimer's disease-type pathology in chimpanzees. J Comp Neurol. 2019;527:1179-1195 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 1d
Wang M, Tang C, Xing R, Liu X, Han X, Liu Y, et al. WDR81 regulates adult hippocampal neurogenesis through endosomal SARA-TGFβ signaling. Mol Psychiatry. 2018;: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:4000; loading ...; fig st2
  • immunocytochemistry; mouse; 1:100; loading ...; fig st2
  • western blot; mouse; 1:1000; loading ...; fig st2
  • immunohistochemistry - paraffin section; human; 1:4000; loading ...; tbl 1
Sundaresan S, Meininger C, Kang A, Photenhauer A, Hayes M, Sahoo N, et al. Gastrin Induces Nuclear Export and Proteasome Degradation of Menin in Enteric Glial Cells. Gastroenterology. 2017;153:1555-1567.e15 pubmed publisher
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3f
Koukouli F, Rooy M, Maskos U. Early and progressive deficit of neuronal activity patterns in a model of local amyloid pathology in mouse prefrontal cortex. Aging (Albany NY). 2016;8:3430-3449 pubmed publisher
  • immunohistochemistry; mouse; 1:1500; loading ...; fig 1g
  • western blot; mouse; 1:6000; loading ...; fig 4a
Vodicka P, Chase K, Iuliano M, Tousley A, Valentine D, Sapp E, et al. Autophagy Activation by Transcription Factor EB (TFEB) in Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:249-260 pubmed
  • immunocytochemistry; mouse; 1:500; loading ...; fig 3d
Huang Z, Hu J, Pan J, Wang Y, Hu G, Zhou J, et al. YAP stabilizes SMAD1 and promotes BMP2-induced neocortical astrocytic differentiation. Development. 2016;143:2398-409 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:1500; loading ...; fig 4b
  • western blot; mouse; 1:6000; loading ...; fig 5a
Vodicka P, Chase K, Iuliano M, Valentine D, Sapp E, Lu B, et al. Effects of Exogenous NUB1 Expression in the Striatum of HDQ175/Q7 Mice. J Huntingtons Dis. 2016;5:163-74 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 3
  • western blot; mouse; 1:1000; fig 6
Sun X, Li L, Liu F, Huang Z, Bean J, Jiao H, et al. Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci. 2016;19:1010-8 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 4
Kim S, Hayashi H, Ishikawa T, Shibata K, Shigetomi E, Shinozaki Y, et al. Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain. J Clin Invest. 2016;126:1983-97 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1000; fig 5
Abdel Hamid A, Firgany A, Ali E. Effect of memantine: A NMDA receptor blocker, on ethambutol-induced retinal injury. Ann Anat. 2016;204:86-92 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 3a
Currais A, Farrokhi C, Dargusch R, Goujon Svrzic M, Maher P. Dietary glycemic index modulates the behavioral and biochemical abnormalities associated with autism spectrum disorder. Mol Psychiatry. 2016;21:426-36 pubmed publisher
  • immunocytochemistry; human; 1:500
Videla Richardson G, Garcia C, Roisman A, Slavutsky I, Fernandez Espinosa D, Romorini L, et al. Specific Preferences in Lineage Choice and Phenotypic Plasticity of Glioma Stem Cells Under BMP4 and Noggin Influence. Brain Pathol. 2016;26:43-61 pubmed publisher
Yin P, Guo X, Yang W, Yan S, Yang S, Zhao T, et al. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol. 2019;137:919-937 pubmed publisher
Park J, Longo F, Park S, Lee S, Bae M, Tyagi R, et al. Inositol polyphosphate multikinase mediates extinction of fear memory. Proc Natl Acad Sci U S A. 2019;116:2707-2712 pubmed publisher
Lee C, Kim H, Lee Y, Kang G, Lim H, Lee S, et al. Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation. Cell Rep. 2018;25:934-946.e5 pubmed publisher
Medina Cano D, Ucuncu E, Nguyen L, Nicouleau M, Lipecka J, Bizot J, et al. High N-glycan multiplicity is critical for neuronal adhesion and sensitizes the developing cerebellum to N-glycosylation defect. elife. 2018;7: pubmed publisher
Hermes D, Xu C, Poklis J, Niphakis M, Cravatt B, Mackie K, et al. Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS. Neuropharmacology. 2018;141:55-65 pubmed publisher
Zuo X, Hou Q, Jin J, Chen X, Zhan L, Tang Y, et al. Inhibition of Cathepsins B Induces Neuroprotection Against Secondary Degeneration in Ipsilateral Substantia Nigra After Focal Cortical Infarction in Adult Male Rats. Front Aging Neurosci. 2018;10:125 pubmed publisher
Hoshi Y, Okabe K, Shibasaki K, Funatsu T, Matsuki N, Ikegaya Y, et al. Ischemic Brain Injury Leads to Brain Edema via Hyperthermia-Induced TRPV4 Activation. J Neurosci. 2018;38:5700-5709 pubmed publisher
Yan S, Tu Z, Liu Z, Fan N, Yang H, Yang S, et al. A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease. Cell. 2018;173:989-1002.e13 pubmed publisher
McGill B, Barve R, Maloney S, Strickland A, Rensing N, Wang P, et al. Abnormal Microglia and Enhanced Inflammation-Related Gene Transcription in Mice with Conditional Deletion of Ctcf in Camk2a-Cre-Expressing Neurons. J Neurosci. 2018;38:200-219 pubmed publisher
Kajstura T, Dougherty S, Linden D. Serotonin axons in the neocortex of the adult female mouse regrow after traumatic brain injury. J Neurosci Res. 2018;96:512-526 pubmed publisher
Sun Y, Lee J, Huang H, Wagner M, Joiner C, Archer D, et al. Sickle Mice Are Sensitive to Hypoxia/Ischemia-Induced Stroke but Respond to Tissue-Type Plasminogen Activator Treatment. Stroke. 2017;48:3347-3355 pubmed publisher
Puissant M, Mouradian G, Liu P, Hodges M. Identifying Candidate Genes that Underlie Cellular pH Sensitivity in Serotonin Neurons Using Transcriptomics: A Potential Role for Kir5.1 Channels. Front Cell Neurosci. 2017;11:34 pubmed publisher
Marins F, Iddings J, Fontes M, Filosa J. Evidence that remodeling of insular cortex neurovascular unit contributes to hypertension-related sympathoexcitation. Physiol Rep. 2017;5: pubmed publisher
Kim J, Ko A, Hyun H, Min S, Kim J. PDI regulates seizure activity via NMDA receptor redox in rats. Sci Rep. 2017;7:42491 pubmed publisher
Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, et al. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. PLoS ONE. 2017;12:e0171947 pubmed publisher
Wofford K, Harris J, Browne K, Brown D, Grovola M, Mietus C, et al. Rapid neuroinflammatory response localized to injured neurons after diffuse traumatic brain injury in swine. Exp Neurol. 2017;290:85-94 pubmed publisher
Halbach M, Gispert S, Stehning T, Damrath E, Walter M, Auburger G. Atxn2 Knockout and CAG42-Knock-in Cerebellum Shows Similarly Dysregulated Expression in Calcium Homeostasis Pathway. Cerebellum. 2017;16:68-81 pubmed publisher
Han W, Umekawa T, Zhou K, Zhang X, Ohshima M, Dominguez C, et al. Cranial irradiation induces transient microglia accumulation, followed by long-lasting inflammation and loss of microglia. Oncotarget. 2016;7:82305-82323 pubmed publisher
Simão D, Terrasso A, Teixeira A, Brito C, Sonnewald U, Alves P. Functional metabolic interactions of human neuron-astrocyte 3D in vitro networks. Sci Rep. 2016;6:33285 pubmed publisher
Wang J, Huang Y, Chiu C, Tweedie D, Luo W, Pick C, et al. Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat. J Neuroinflammation. 2016;13:168 pubmed publisher
Viana da Silva S, Haberl M, Zhang P, Bethge P, Lemos C, Gonçalves N, et al. Early synaptic deficits in the APP/PS1 mouse model of Alzheimer's disease involve neuronal adenosine A2A receptors. Nat Commun. 2016;7:11915 pubmed publisher
Prange Kiel J, Dudzinski D, Prols F, Glatzel M, Matschke J, Rune G. Aromatase Expression in the Hippocampus of AD Patients and 5xFAD Mice. Neural Plast. 2016;2016:9802086 pubmed publisher
Morita J, Kano K, Kato K, Takita H, Sakagami H, Yamamoto Y, et al. Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase. Sci Rep. 2016;6:20995 pubmed publisher
Dietl S, Schwinn S, Dietl S, Riedel S, Deinlein F, Rutkowski S, et al. MB3W1 is an orthotopic xenograft model for anaplastic medulloblastoma displaying cancer stem cell- and Group 3-properties. BMC Cancer. 2016;16:115 pubmed publisher
Sedeyn J, Wu H, Hobbs R, Levin E, Nagele R, Venkataraman V. Histamine Induces Alzheimer's Disease-Like Blood Brain Barrier Breach and Local Cellular Responses in Mouse Brain Organotypic Cultures. Biomed Res Int. 2015;2015:937148 pubmed publisher
Pereira T, Gärtner A, Amorim I, Almeida A, Caseiro A, Armada Da silva P, et al. Promoting nerve regeneration in a neurotmesis rat model using poly(DL-lactide-ε-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly: in vitro and in vivo analysis. Biomed Res Int. 2014;2014:302659 pubmed publisher
Wang X, Hu J, She Y, Smith G, Xu X. Cortical PKC inhibition promotes axonal regeneration of the corticospinal tract and forelimb functional recovery after cervical dorsal spinal hemisection in adult rats. Cereb Cortex. 2014;24:3069-79 pubmed publisher
product information
Catalog Number :
AB5804
Subcategory :
Neuroscience
Product Name :
Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
Q28115
Host Name :
Rabbit
Antigen :
Glial Fibrillary Acidic Protein (GFAP)
Conjugate :
Serum
Product Description :
Anti-Glial Fibrillary Acidic Protein (GFAP) Antibody
Cross Reactivity :
Bovine;Canine;Human;Rat
Background :
Glial fibrillary acidic protein is a class-III intermediate filament. GFAP is the main constituent of intermediate filaments in astrocytes and serves as a cell specific marker that distinguishes differentiated astrocytes from other glial cells during the development of the central nervous system.
ALT Names :
glial fibrillary acidic protein
Immunogen :
Purified bovine GFAP
Specificity :
Recognizes Glial Fibrillary Acidic Protein (GFAP).
Package Size :
50 µL
Uses :
Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin)
Storage :
Stable for 1 year at -20°C undiluted aliquots from date of receipt. Handling Recommendations: Upon receipt, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
more info or order :
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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