Nanog Antibody, NT | EMD Millipore AB5731 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Nanog Antibody, NT

catalog :

AB5731

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ChIP-Seq

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; fig 1	Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, Matsuda E. CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells. Sci Rep. 2016;6:34188 pubmed publisher
western blot; mouse; 1:1000; fig 2	Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed publisher
ChIP-Seq; mouse; fig st2	Stelloh C, Reimer M, Pulakanti K, Blinka S, Peterson J, Pinello L, et al. The cohesin-associated protein Wapal is required for proper Polycomb-mediated gene silencing. Epigenetics Chromatin. 2016;9:14 pubmed publisher
	Jiao C, Meng T, Zhou C, Wang X, Wang P, Lu M, et al. TGF-β signaling regulates SPOP expression and promotes prostate cancer cell stemness. Aging (Albany NY). 2020;12:7747-7760 pubmed publisher
	Xu W, Li J, Li L, Hou T, Cai X, Liu T, et al. FOXD3 Suppresses Tumor-Initiating Features in Lung Cancer via Transcriptional Repression of WDR5. Stem Cells. 2019;37:582-592 pubmed publisher
	Tang S, Fang Y, Huang G, Xu X, Padilla Banks E, Fan W, et al. Methionine metabolism is essential for SIRT1-regulated mouse embryonic stem cell maintenance and embryonic development. EMBO J. 2017;36:3175-3193 pubmed publisher
	MÃ¼nst B, Thier M, WinnemÃ¶ller D, Helfen M, Thummer R, Edenhofer F. Nanog induces suppression of senescence through downregulation of p27KIP1 expression. J Cell Sci. 2016;129:912-20 pubmed publisher

product information

Catalog Number :

AB5731

Subcategory :

Stem Cell Research

Product Name :

Anti-Nanog Antibody, NT

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9H9S0

Host Name :

Rabbit

Antigen :

Nanog

Conjugate :

Affinity Purified

Isotype :

IgG

Product Description :

Anti-Nanog Antibody, NT

Cross Reactivity :

Human;Mouse;Rat

Background :

NANOG is a gene expressed in embryonic stem cells (ESCs) and is thought to be a key factor in maintaining pluripotency. NANOG thought to function in concert with other factors such as POU5F1 and SOX2 to establish ESC identity. These cells offer an important area of study because of their ability to maintain pluripotency, i.e., these cells have the ability to become virtually any cell of any of the three germ layers (endoderm, ectoderm, mesoderm). NANOG may be useful in the immunohistochemical diagnosis of tumors. NANOG is expressed in germ cells of the fetus and in some germ cell tumors of the gonads and central nervous system (CNS).

ALT Names :

Homeobox transcription factor Nanog;Nanog homeobox

Immunogen :

Synthetic peptide from mouse Nanog.

Specificity :

Antibody recognizes Nanog.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Stable at 2-8°C in undiluted aliquots for up to 6 months from date of receipt.