HES-1 Antibody | EMD Millipore AB5702 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

HES-1 Antibody

catalog :

AB5702

quantity :

100 μg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 2b	Krepler C, Xiao M, Samanta M, Vultur A, Chen H, Brafford P, et al. Targeting Notch enhances the efficacy of ERK inhibitors in BRAF-V600E melanoma. Oncotarget. 2016;7:71211-71222 pubmed publisher
	Tremblay C, Huang F, Levesque G, Carreau M. Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity. BMC Res Notes. 2018;11:138 pubmed publisher
	Kabraji S, SolÃ© X, Huang Y, Bango C, Bowden M, Bardia A, et al. AKT1low quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer. Breast Cancer Res. 2017;19:88 pubmed publisher
	Zygmunt D, Singhal N, Kim M, Cramer M, Crowe K, Xu R, et al. Deletion of Pofut1 in Mouse Skeletal Myofibers Induces Muscle Aging-Related Phenotypes in cis and in trans. Mol Cell Biol. 2017;37: pubmed publisher

product information

Catalog Number :

AB5702

Subcategory :

Neuroscience

Product Name :

Anti-HES-1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q14469

Host Name :

Rabbit

Antigen :

HES-1

Conjugate :

Affinity Purified

Product Description :

Anti-HES-1 Antibody

Cross Reactivity :

Human;Mouse

Background :

Hes1 is a transcriptional repressor of genes that require a bHLH protein for their transcription. It may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Hes1 is expressed in developing neuroectodermal and endodermal endocrine tissues, and Hes1 deficient embryos show severe defects in neuronal development, as well as pancreatic hypoplasia.

ALT Names :

Hairy 1

Immunogen :

Synthetic peptide

Specificity :

Recognizes HES-1 (Hairy family), a Helix-loop-helix class of transcription factor.

Package Size :

100 μg

Uses :

Immunohistochemistry;Western Blotting

Storage :

Stable for 1 year at -80ºC from date of receipt.