| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; 1:3000; loading ...; fig 1
| Marks C, Shonesy B, Wang X, Stephenson J, Niswender C, Colbran R. Activated CaMKIIα Binds to the mGlu5 Metabotropic Glutamate Receptor and Modulates Calcium Mobilization. Mol Pharmacol. 2018;94:1352-1362 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 1d
| Lautz J, Brown E, Williams VanSchoiack A, Smith S. Synaptic activity induces input-specific rearrangements in a targeted synaptic protein interaction network. J Neurochem. 2018;146:540-559 pubmed publisher |
- immunocytochemistry; mouse; 1:50; fig 2h
| Achuta V, Grym H, Putkonen N, Louhivuori V, Kärkkäinen V, Koistinaho J, et al. Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome. Dev Neurobiol. 2017;77:438-453 pubmed publisher |
| Yokoi N, Fukata Y, Sekiya A, Murakami T, Kobayashi K, Fukata M. Identification of PSD-95 Depalmitoylating Enzymes. J Neurosci. 2016;36:6431-44 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Vicidomini C, Ponzoni L, Lim D, Schmeisser M, Reim D, Morello N, et al. Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice. Mol Psychiatry. 2017;22:689-702 pubmed publisher |
- western blot; mouse; 1:1000; fig 7a
| Shih Y, Hsueh Y. VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun. 2016;7:11020 pubmed publisher |
- other; rat; 1:400; fig 1
- immunohistochemistry - free floating section; rat; 1:500; fig s2
- immunocytochemistry; rat; 1:250; fig 1
- western blot; rat; 1:1000; fig 1
| Vincent K, Cornea V, Jong Y, Laferriere A, Kumar N, Mickeviciute A, et al. Intracellular mGluR5 plays a critical role in neuropathic pain. Nat Commun. 2016;7:10604 pubmed publisher |
| Scheefhals N, Catsburg L, Westerveld M, Blanpied T, Hoogenraad C, MacGillavry H. Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5. Cell Rep. 2019;29:258-269.e8 pubmed publisher |
| Chokshi V, Gao M, Grier B, Owens A, Wang H, Worley P, et al. Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling. Neuron. 2019;104:736-748.e6 pubmed publisher |
| Holz A, Mülsch F, Schwarz M, Hollmann M, Dobrossy M, Coenen V, et al. Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation. Neuron. 2019;104:338-352.e7 pubmed publisher |
| Umpierre A, West P, White J, Wilcox K. Conditional Knock-out of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake. J Neurosci. 2019;39:727-742 pubmed publisher |
| Brown E, Lautz J, Davis T, Gniffke E, VanSchoiack A, Neier S, et al. Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models. Mol Autism. 2018;9:48 pubmed publisher |
| Zuena A, Iacovelli L, Orlando R, Di Menna L, Casolini P, Alemà G, et al. In Vivo Non-radioactive Assessment of mGlu5 Receptor-Activated Polyphosphoinositide Hydrolysis in Response to Systemic Administration of a Positive Allosteric Modulator. Front Pharmacol. 2018;9:804 pubmed publisher |
| Doria J, de Souza J, Silva F, Olmo I, Carvalho T, Alves Silva J, et al. The mGluR5 positive allosteric modulator VU0409551 improves synaptic plasticity and memory of a mouse model of Huntington's disease. J Neurochem. 2018;147:222-239 pubmed publisher |
| Heise C, Preuss J, Schroeder J, Battaglia C, Kolibius J, Schmid R, et al. Heterogeneity of Cell Surface Glutamate and GABA Receptor Expression in Shank and CNTN4 Autism Mouse Models. Front Mol Neurosci. 2018;11:212 pubmed publisher |
| Wall M, Collins D, Chery S, Allen Z, Pastuzyn E, George A, et al. The Temporal Dynamics of Arc Expression Regulate Cognitive Flexibility. Neuron. 2018;98:1124-1132.e7 pubmed publisher |
| Li Y, Kim R, Cho Y, Song W, Kim D, Kim K, et al. Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response. J Neurosci. 2018;38:5872-5887 pubmed publisher |
| Abd Elrahman K, Hamilton A, Vasefi M, Ferguson S. Autophagy is increased following either pharmacological or genetic silencing of mGluR5 signaling in Alzheimer's disease mouse models. Mol Brain. 2018;11:19 pubmed publisher |
| Nardecchia F, Orlando R, Iacovelli L, Colamartino M, Fiori E, Leuzzi V, et al. Targeting mGlu5 Metabotropic Glutamate Receptors in the Treatment of Cognitive Dysfunction in a Mouse Model of Phenylketonuria. Front Neurosci. 2018;12:154 pubmed publisher |
| Cortese G, Olin A, O Riordan K, Hullinger R, Burger C. Environmental enrichment improves hippocampal function in aged rats by enhancing learning and memory, LTP, and mGluR5-Homer1c activity. Neurobiol Aging. 2018;63:1-11 pubmed publisher |
| Di Menna L, Joffe M, Iacovelli L, Orlando R, Lindsley C, Mairesse J, et al. Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system. Neuropharmacology. 2018;128:301-313 pubmed publisher |
| Loweth J, Scheyer A, Milovanovic M, Lacrosse A, Flores Barrera E, Werner C, et al. Synaptic depression via mGluR1 positive allosteric modulation suppresses cue-induced cocaine craving. Nat Neurosci. 2014;17:73-80 pubmed publisher |
