Growth Associated Protein 43 Antibody | EMD Millipore AB5312 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Growth Associated Protein 43 Antibody

catalog :

AB5312

quantity :

100 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

product information

Catalog Number :

AB5312

Subcategory :

Neuroscience

Product Name :

Anti-Growth Associated Protein 43 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P17677

Host Name :

Rabbit

Antigen :

Growth Associated Protein 43

Conjugate :

Serum

Product Description :

Anti-Growth Associated Protein 43 Antibody

Cross Reactivity :

Bovine;Human;Mouse;Monkey;Rat;Feline

Background :

GAP-43, a common marker of differentiating neurons, is expressed at elevated levels by developing or regenerating neurons during axon growth. While GAP-43 is an integral membrane protein associated with the cytoplasmic surface of axonal growth cones (and synapses), it is absent from dendritic growth cones. In adult brain, GAP-43 is found in high concentration in presynaptic areas where memory formation is thought to occur, such as frontal cortex, limbic system and hippocampus. Phosphorylation of GAP-43 by PKC (at Ser41 on human, mouse, rat, and bovine GAP-43 or Ser42 on chicken and Xenopus GAP-43) is specifically correlated with certain forms of synaptic plasticity.

ALT Names :

GAP-43; Neuromodulin; B-50

Immunogen :

Purified GAP-43 from feline brain (McIntosh and Parkinson, 1990).

Specificity :

AB5312 specifically recognizes GAP-43 regardless of the protein's phosphorylation state. This antiserum has been refered to in the literature as CG-1.

Package Size :

100 μL

Uses :

Immunocytochemistry;Immunohistochemistry;Immunohistochemistry (Paraffin);Immunoprecipitation;Western Blotting

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.