Growth Associated Protein-43 (GAP-43) Antibody | EMD Millipore AB5220 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Growth Associated Protein-43 (GAP-43) Antibody

catalog :

AB5220

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, dogs, chicken, bovine

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:1000; loading ...; fig 1a	Yu J, Chen M, Huang H, Zhu J, Song H, Zhu J, et al. Dynamic m6A modification regulates local translation of mRNA in axons. Nucleic Acids Res. 2018;46:1412-1423 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 5e	Kilpatrick C, Murakami S, Feng M, Wu X, Lal R, Chen G, et al. Dissociation of Golgi-associated DHHC-type Zinc Finger Protein (GODZ)- and Sertoli Cell Gene with a Zinc Finger Domain-? (SERZ-?)-mediated Palmitoylation by Loss of Function Analyses in Knock-out Mice. J Biol Chem. 2016;291:27371-27386 pubmed publisher
immunocytochemistry; mouse; 1:500; fig 1	Skytt D, Toft Kehler A, Brændstrup C, Cejvanovic S, Gurubaran I, Bergersen L, et al. Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Müller Cells and Retinal Ganglion Cells. Biomed Res Int. 2016;2016:1087647 pubmed publisher
immunohistochemistry - paraffin section; dogs; 1:600; fig s1	Spitzbarth I, Lempp C, Kegler K, Ulrich R, Kalkuhl A, Deschl U, et al. Immunohistochemical and transcriptome analyses indicate complex breakdown of axonal transport mechanisms in canine distemper leukoencephalitis. Brain Behav. 2016;6:e00472 pubmed publisher
immunohistochemistry - frozen section; rat; 1:500; fig 3	Keilhoff G, Lucas B, Uhde K, Fansa H. Selected gene profiles of stressed NSC-34 cells and rat spinal cord following peripheral nerve reconstruction and minocycline treatment. Exp Ther Med. 2016;11:1685-1699 pubmed
immunocytochemistry; human; fig 3 western blot; human; fig 1	Morales HernÃ¡ndez A, GonzÃ¡lez Rico F, RomÃ¡n A, Rico Leo E, Alvarez Barrientos A, SÃ¡nchez L, et al. Alu retrotransposons promote differentiation of human carcinoma cells through the aryl hydrocarbon receptor. Nucleic Acids Res. 2016;44:4665-83 pubmed publisher
	Zhang Z, Yang D, Zhang M, Zhu N, Zhou Y, Storm D, et al. Deletion of Type 3 Adenylyl Cyclase Perturbs the Postnatal Maturation of Olfactory Sensory Neurons and Olfactory Cilium Ultrastructure in Mice. Front Cell Neurosci. 2017;11:1 pubmed publisher
	Ferguson C, Zhao H. Simultaneous Loss of NCKX4 and CNG Channel Desensitization Impairs Olfactory Sensitivity. J Neurosci. 2017;37:110-119 pubmed publisher
	Oprych K, Cotfas D, Choi D. Common olfactory ensheathing glial markers in the developing human olfactory system. Brain Struct Funct. 2017;222:1877-1895 pubmed publisher
	Campos C, Cangussú S, Duz A, Cartelle C, Noviello M, Veloso V, et al. Enteric Neuronal Damage, Intramuscular Denervation and Smooth Muscle Phenotype Changes as Mechanisms of Chagasic Megacolon: Evidence from a Long-Term Murine Model of Trypanosoma cruzi Infection. PLoS ONE. 2016;11:e0153038 pubmed publisher
	Iaci J, Parry T, Huang Z, Pavlopoulos E, Finklestein S, Ren J, et al. An optimized dosing regimen of cimaglermin (neuregulin 1Î²3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats. J Neurosci Res. 2016;94:253-65 pubmed publisher
	Pereira T, GÃ¤rtner A, Amorim I, Almeida A, Caseiro A, Armada Da silva P, et al. Promoting nerve regeneration in a neurotmesis rat model using poly(DL-lactide-Îµ-caprolactone) membranes and mesenchymal stem cells from the Wharton's jelly: in vitro and in vivo analysis. Biomed Res Int. 2014;2014:302659 pubmed publisher

product information

Catalog Number :

AB5220

Subcategory :

Neuroscience

Product Name :

Anti-Growth Associated Protein-43 (GAP-43) Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P17677

Host Name :

Rabbit

Antigen :

Growth Associated Protein-43 (GAP-43)

Conjugate :

Purified

Product Description :

Anti-Growth Associated Protein-43 (GAP-43) Antibody

Cross Reactivity :

Human;Mouse;Rat;Chicken;Bovine

Background :

GAP-43, a common marker of differentiating neurons, is expressed at elevated levels by developing or regenerating neurons during axon growth. While GAP-43 is an integral membrane protein associated with the cytoplasmic surface of axonal growth cones (and synapses), it is absent from dendritic growth cones. In adult brain, GAP-43 is found in high concentration in presynaptic areas where memory formation is thought to occur, such as frontal cortex, limbic system and hippocampus. Phosphorylation of GAP-43 by PKC (at Ser41 on human, mouse, rat, and bovine GAP-43 or Ser42 on chicken and Xenopus GAP-43) is specifically correlated with certain forms of synaptic plasticity.

ALT Names :

Neuromodulin

Immunogen :

Recombinant rat GAP-43 (complete sequence).

Specificity :

Recognizes Growth Associated Protein-43 (GAP-43).

Package Size :

100 µL

Uses :

ELISA;Immunocytochemistry;Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for up to 6 months at -20ºC in undiluted aliquots from date of receipt. Avoid repeated freeze/thaw cycles. During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container’s cap.