Parkin Antibody, a.a. 305-323 | EMD Millipore AB5112 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Parkin Antibody, a.a. 305-323

catalog :

AB5112

quantity :

50 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, ELISA, immunohistochemistry

citations: 2

Reference
Huang T, Hsueh Y. Calcium/calmodulin-dependent serine protein kinase (CASK), a protein implicated in mental retardation and autism-spectrum disorders, interacts with T-Brain-1 (TBR1) to control extinction of associative memory in male mice. J Psychiatry Neurosci. 2017;42:37-47 pubmed
Scuderi S, La Cognata V, Drago F, Cavallaro S, D Agata V. Alternative splicing generates different parkin protein isoforms: evidences in human, rat, and mouse brain. Biomed Res Int. 2014;2014:690796 pubmed publisher

product information

Catalog Number :

AB5112

Subcategory :

Neuroscience

Product Name :

Anti-Parkin Antibody, a.a. 305-323

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

O60260

Host Name :

Rabbit

Antigen :

Parkin

Conjugate :

Serum

Product Description :

Anti-Parkin Antibody, a.a. 305-323

Cross Reactivity :

Human;Rat

Immunogen :

A 19 amino acid peptide (RILGEEQYNRYQQYGAEEC) corresponding to amino acids 305-323 of the human parkin molecule. An internal peptide sequence was chosen to avoid the possibility of cross reactivity with ubiquitin.

Specificity :

Parkin. Parkinson's disease is a common neurodegenerative disease is caused by slow death of neurons in the substantial nigra, a brain region that utilizes the neurotransmitter dopamine. Parkin, a recently discovered gene encoding a large protein, may be involved in normal and abnormal protein degradation in cells. Recent evidence indicates that point mutations in the Parkin gene appear to be responsible for the pathogenesis of some forms of Parkinson's disease.

Package Size :

50 µL

Uses :

ELISA;Western Blotting;Immunohistochemistry

Storage :

Maintain lyophilized material at at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (ACS grade or better) can be added (1:1) for greater stability.