Amyloid Antibody, β 1-40/42 | EMD Millipore AB5076 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Amyloid Antibody, β 1-40/42

catalog :

AB5076

quantity :

50 μL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; fig 7b	Honarpisheh P, Reynolds C, Blasco Conesa M, Moruno Manchon J, Putluri N, Bhattacharjee M, et al. Dysregulated Gut Homeostasis Observed Prior to the Accumulation of the Brain Amyloid-β in Tg2576 Mice. Int J Mol Sci. 2020;21: pubmed publisher
immunohistochemistry - paraffin section; human; loading ...; fig 4	Zhan X, Stamova B, Jin L, DeCarli C, Phinney B, Sharp F. Gram-negative bacterial molecules associate with Alzheimer disease pathology. Neurology. 2016;87:2324-2332 pubmed

product information

Catalog Number :

AB5076

Subcategory :

Neuroscience

Product Name :

Anti-Amyloid Antibody, β 1-40/42

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P05067

Host Name :

Rabbit

Antigen :

Amyloid

Conjugate :

Serum

Product Description :

Anti-Amyloid Antibody, β 1-40/42

Cross Reactivity :

Human;Mouse

Immunogen :

A synthetic beta-amyloid peptide 1-40 conjugated to BSA.

Specificity :

Recognizes beta-amyloid 1-40/42. One of the most important and initial steps which causes loss of memory and cognition in Alzheimer's Disease (AD) involves proteolytic cleavage of amyloid precursor protein (APP, chromosome 21) releasing short 40, 42 & 43 amino acid peptides (beta amyloid 1-40, 1-42 and 1-43). Polymerization of beta-amyloid and subsequent neuronal deposit (amyloid) leads to the degeneration of neurons involved in memory and cognition. The immunogen peptide shows homology with beta-amyloid 1-28 and beta-amyloid 12-28. No cross reactivity is observed with CGRP.

Package Size :

50 μL

Uses :

ELISA;Immunohistochemistry;Western Blotting

Storage :

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.