Substance P Receptor Antibody, pain | EMD Millipore AB5060 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Substance P Receptor Antibody, pain

catalog :

AB5060

quantity :

50 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 5

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:1000; fig 3e	Alshawaf A, Viventi S, Qiu W, D Abaco G, Nayagam B, Erlichster M, et al. Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. Sci Rep. 2018;8:603 pubmed publisher
	Salib M, Joshi A, Katona L, Howarth M, Micklem B, Somogyi P, et al. GABAergic Medial Septal Neurons with Low-Rhythmic Firing Innervating the Dentate Gyrus and Hippocampal Area CA3. J Neurosci. 2019;39:4527-4549 pubmed publisher
	Chen W, Ennes H, McRoberts J, Marvizon J. Mechanisms of μ-opioid receptor inhibition of NMDA receptor-induced substance P release in the rat spinal cord. Neuropharmacology. 2018;128:255-268 pubmed publisher
	Xin D, Hadrevi J, Elliott M, Amin M, Harris M, Barr Gillespie A, et al. Effectiveness of conservative interventions for sickness and pain behaviors induced by a high repetition high force upper extremity task. BMC Neurosci. 2017;18:36 pubmed publisher
	Tochiki K, MaiarÃº M, Norris C, Hunt S, GÃ©ranton S. The mitogen and stress-activated protein kinase 1 regulates the rapid epigenetic tagging of dorsal horn neurons and nocifensive behaviour. Pain. 2016;157:2594-2604 pubmed

product information

Catalog Number :

AB5060

Subcategory :

Neuroscience

Product Name :

Anti-Substance P Receptor Antibody, pain

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P20366

Host Name :

Rabbit

Antigen :

Substance P Receptor

Conjugate :

Serum

Product Description :

Anti-Substance P Receptor Antibody, pain

Cross Reactivity :

Guinea Pig;Mouse;Rat

Background :

Substance P is a tachykinin family neuropeptide that functions as a neurotransmitter and neuromodulator. In the CNS, Substance P is involved in the regulation of mood, anxiety, sleep, saiety, reinforcement, respiratory rhythm and pain processing. In nociception, the neuropeptide is released at local spinal cord synapses. Recent research now shows substance P is potentially involved in endothelial cell differentiation as well as diverse roles in neuroinflammatory response. The endogenous receptor for Substance P is neurokinin 1 receptor (NK1 receptor), which belongs to the tachykinin receptor sub-family of GPCRs.

ALT Names :

NK-1 Receptor

Immunogen :

Synthetic peptide that corresponds to a 23 amino acid sequence (385-407) of the COOH terminus of the rat Substance P Receptor (NK-1).

Specificity :

Specific for the Substance P Receptor (NK-1).

Package Size :

50 µL

Uses :

Immunofluorescence;Immunohistochemistry;Western Blotting

Storage :

Stable for 1 year at -20ºC from date of receipt.