PARP Cleaved Form Antibody | EMD Millipore AB3620 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PARP Cleaved Form Antibody

catalog :

AB3620

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

product information

Catalog Number :

AB3620

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-PARP Cleaved Form Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P09874

Host Name :

Rabbit

Antigen :

PARP Cleaved Form

Conjugate :

Purified

Product Description :

Anti-PARP Cleaved Form Antibody

Cross Reactivity :

Human

Background :

PARP, a 116 kDa poly ADP-ribose polymerase, is a conserved nuclear enzyme implicated in DNA repair and in the apoptosis response. This protein is one of the main in vivo cleavage targets of caspase-3. PARP is cleaved into two fragments: its N-terminal 24 kDa fragment, containing its DNA binding domain, and its C-terminal 89 kDa catalytic domain.

ALT Names :

Poly [ADP-ribose] polymerase 1;PARP-1;NAD(+) ADP-ribosyltransferase 1;ADPRT 1;Poly[ADP-ribose] synthase 1;ARTD1

Immunogen :

Synthetic peptide

Specificity :

AB3620 detects only the cleaved large 89kDa subunit of human PARP and does not detect the full length PARP. The immunogen sequence is not strongly conserved between human, mouse and rat.

Package Size :

50 µg

Uses :

Western Blotting

Storage :

Maintain frozen at -20°C. For optimal storage, aliquot and freeze at -20°C to -70°C. Avoid repeated freeze/thaw cycles.