ASC Antibody | EMD Millipore AB3607 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

ASC Antibody

catalog :

AB3607

quantity :

100 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4b	Xing Y, Cao R, Hu H. TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles). Cell Death Dis. 2016;7:e2322 pubmed publisher

product information

Catalog Number :

AB3607

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-ASC Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

Q9ULZ3

Host Name :

Rabbit

Antigen :

ASC

Conjugate :

Purified

Product Description :

Anti-ASC Antibody

Cross Reactivity :

Human

Background :

Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, Bcl10, Apaf-1, ARC, caspase-2 and caspase-9. A novel CARD domain containing protein has been identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells. Overexpression of ASC/TMS1 induced DNA fragmentation. ASC/TMS1 is expressed in a variety of human and mouse tissues.

ALT Names :

TMS1; CARD5; Apoptosis-associated Speck-like Protein containing a CARD

Immunogen :

Peptide corresponding to aa 182-195 (RESQSYLVEDLERS) of human ASC.

Specificity :

Detects a 25 kDa band by western blot, corresponding to ASC/TMS1.

Package Size :

100 µg

Uses :

Western Blotting

Storage :

Maintain at 4°C for up to 6 months.