Aquaporin 4 Antibody, CT | EMD Millipore AB3594-200UL product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Aquaporin 4 Antibody, CT

catalog :

AB3594-200UL

quantity :

200 µL

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, cow

application :

western blot, immunohistochemistry

product information

Catalog Number :

AB3594-200UL

Subcategory :

Neuroscience

Product Name :

Anti-Aquaporin 4 Antibody, CT

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P55087

Host Name :

Rabbit

Antigen :

Aquaporin 4

Conjugate :

Purified

Product Description :

Anti-Aquaporin 4 Antibody, CT

Cross Reactivity :

Human;Mouse;Rat

Background :

Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special proteins "aquaporins". Aquaporins, are integral membrane proteins from a larger family of major intrinsic proteins (MIP) that form pores in the membrane of biological cells. Over the last decade, genes for several members of aquaporin family have been cloned, expressed, and their distribution studied in many tissues. The water-specific channel Aquaporin 4 is located in various tissues including the gastrointestinal tract, kidney and brain. It is an osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. In CNS tissue, AQP4 localizes to astrocyte endfeet making it a useful structural marker.

ALT Names :

Mercurial-Insensitive Water Channel

Immunogen :

GST fusion protein with residues 249-323 of rat Aquaporin 4 (SwissProt accession number P47863).

Specificity :

Recognizes Aquaporin 4 (AQP4, WCH4, Mercurial-Insensitive Water Channel).

Package Size :

200 µL

Uses :

Immunohistochemistry;Western Blotting

Storage :

Stable for up to 6 months at -20ºC from date of receipt. After reconstitution stable at -20ºC in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.