Monocarboxylate Transporter 1 Antibody | EMD Millipore AB3538P product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Monocarboxylate Transporter 1 Antibody

catalog :

AB3538P

quantity :

50 µg

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; loading ...; fig 2a, e7a	Tasdogan A, Faubert B, Ramesh V, Ubellacker J, Shen B, Solmonson A, et al. Metabolic heterogeneity confers differences in melanoma metastatic potential. Nature. 2020;577:115-120 pubmed publisher
western blot; human; loading ...; fig 3	Brocherie F, Millet G, D Hulst G, Van Thienen R, Deldicque L, Girard O. Repeated maximal-intensity hypoxic exercise superimposed to hypoxic residence boosts skeletal muscle transcriptional responses in elite team-sport athletes. Acta Physiol (Oxf). 2018;222: pubmed publisher
western blot; human; loading ...; fig 1a	Dovmark T, Saccomano M, Hulikova A, Alves F, Swietach P. Connexin-43 channels are a pathway for discharging lactate from glycolytic pancreatic ductal adenocarcinoma cells. Oncogene. 2017;36:4538-4550 pubmed publisher
immunohistochemistry; human; 1:300; fig 1	Martins S, Amorim R, Viana Pereira M, Pinheiro C, Costa R, Silva P, et al. Significance of glycolytic metabolism-related protein expression in colorectal cancer, lymph node and hepatic metastasis. BMC Cancer. 2016;16:535 pubmed publisher
immunocytochemistry; human; fig 2 western blot; human; 1:500; fig 5	Eichner R, Heider M, Fernández Sáiz V, van Bebber F, Garz A, Lemeer S, et al. Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity. Nat Med. 2016;22:735-43 pubmed publisher
immunohistochemistry - paraffin section; human; fig 2 western blot; human; fig 3	Andersen A, Flinck M, Oernbo E, Pedersen N, Viuff B, Pedersen S. Roles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment. Mol Cancer. 2016;15:45 pubmed publisher
western blot; human; 1:500; fig 2	Vorup J, Tybirk J, Gunnarsson T, Ravnholt T, Dalsgaard S, Bangsbo J. Effect of speed endurance and strength training on performance, running economy and muscular adaptations in endurance-trained runners. Eur J Appl Physiol. 2016;116:1331-41 pubmed publisher
western blot; human; fig 1	Mohr M, Thomassen M, Girard O, Racinais S, Nybo L. Muscle variables of importance for physiological performance in competitive football. Eur J Appl Physiol. 2016;116:251-62 pubmed publisher
	Alves W, Bonatelli M, Dufloth R, Kerr L, Carrara G, da Costa R, et al. CAIX is a predictor of pathological complete response and is associated with higher survival in locally advanced breast cancer submitted to neoadjuvant chemotherapy. BMC Cancer. 2019;19:1173 pubmed publisher
	Solís Maldonado M, Miró M, Acuña A, Covarrubias Pinto A, Loaiza A, Mayorga G, et al. Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression. CNS Neurosci Ther. 2018;24:343-352 pubmed publisher
	Payen V, Hsu M, RÃ¤decke K, Wyart E, Vazeille T, Bouzin C, et al. Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter. Cancer Res. 2017;77:5591-5601 pubmed publisher
	Van HÃ©e V, Labar D, Dehon G, Grasso D, GrÃ©goire V, Muccioli G, et al. Radiosynthesis and validation of (Â±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors. Oncotarget. 2017;8:24415-24428 pubmed publisher

product information

Catalog Number :

AB3538P

Subcategory :

Neuroscience

Product Name :

Anti-Monocarboxylate Transporter 1 Antibody

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P53985

Host Name :

Rabbit

Antigen :

Monocarboxylate Transporter 1

Conjugate :

Affinity Purified

Product Description :

Anti-Monocarboxylate Transporter 1 Antibody

Cross Reactivity :

Human

ALT Names :

MCT1

Immunogen :

A 15 amino acid peptide sequence near the C-terminus of human MCT1 (Gerhart et al. 1997; Knott et al. 1999; Takanaga et al. 1995; Carpenter et al. 1996; Koehler-Stec et al. 1998; Yoon et al. 1999; Halestrap & Price 1999).

Specificity :

Recognizes human Monocarboxylate Transporter 1 (MCT1). The immunogen shows no significant sequence homology with MCT2-8.

Package Size :

50 µg

Uses :

ELISA;Western Blotting

Storage :

Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.