product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
PGC-1 Antibody
catalog :
AB3242
quantity :
100 μl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig s4d
Hogarth M, Houweling P, Thomas K, Gordish Dressman H, Bello L, Pegoraro E, et al. Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy. Nat Commun. 2017;8:14143 pubmed publisher
  • western blot; human; loading ...; fig 3a
Zou P, Liu L, Zheng L, Payne K, Manjili M, Idowu M, et al. Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment. Oxid Med Cell Longev. 2016;2016:4085727 pubmed
van Veen J, Scherzer M, Boshuizen J, Chu M, Liu A, Landman A, et al. Mutationally-activated PI3'-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase. elife. 2019;8: pubmed publisher
Rojas Morales P, Tapia E, León Contreras J, González Reyes S, Jiménez Osorio A, Trujillo J, et al. Mechanisms of Fasting-Mediated Protection against Renal Injury and Fibrosis Development after Ischemic Acute Kidney Injury. Biomolecules. 2019;9: pubmed publisher
Cui A, Fan H, Zhang Y, Zhang Y, Niu D, Liu S, et al. Dexamethasone-induced Krüppel-like factor 9 expression promotes hepatic gluconeogenesis and hyperglycemia. J Clin Invest. 2019;129:2266-2278 pubmed publisher
O Brien K, Horscroft J, Devaux J, Lindsay R, Steel A, Clark A, et al. PPARα-independent effects of nitrate supplementation on skeletal muscle metabolism in hypoxia. Biochim Biophys Acta Mol Basis Dis. 2019;1865:844-853 pubmed publisher
Yamanishi K, Maeda S, Kuwahara Otani S, Hashimoto T, Ikubo K, Mukai K, et al. Deficiency in interleukin-18 promotes differentiation of brown adipose tissue resulting in fat accumulation despite dyslipidemia. J Transl Med. 2018;16:314 pubmed publisher
Zhang L, Ip C, Lee I, Qi Y, Reed F, Karl T, et al. Diet-induced adaptive thermogenesis requires neuropeptide FF receptor-2 signalling. Nat Commun. 2018;9:4722 pubmed publisher
Chen C, Erlich A, Hood D. Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle. Skelet Muscle. 2018;8:10 pubmed publisher
Wang X, Luo Y, Wang D, Adorini L, Pruzanski M, Dobrinskikh E, et al. A dual agonist of farnesoid X receptor (FXR) and the G protein-coupled receptor TGR5, INT-767, reverses age-related kidney disease in mice. J Biol Chem. 2017;292:12018-12024 pubmed publisher
Soofi A, Wolf K, Emont M, Qi N, Martinez Santibañez G, Grimley E, et al. The kielin/chordin-like protein (KCP) attenuates high-fat diet-induced obesity and metabolic syndrome in mice. J Biol Chem. 2017;292:9051-9062 pubmed publisher
Ay M, Luo J, Langley M, Jin H, Anantharam V, Kanthasamy A, et al. Molecular mechanisms underlying protective effects of quercetin against mitochondrial dysfunction and progressive dopaminergic neurodegeneration in cell culture and MitoPark transgenic mouse models of Parkinson's Disease. J Neurochem. 2017;141:766-782 pubmed publisher
Macmillan N, Kapchinsky S, Konokhova Y, Gouspillou G, de Sousa Sena R, Jagoe R, et al. Eccentric Ergometer Training Promotes Locomotor Muscle Strength but Not Mitochondrial Adaptation in Patients with Severe Chronic Obstructive Pulmonary Disease. Front Physiol. 2017;8:114 pubmed publisher
Zhu Q, Ghoshal S, Tyagi R, Chakraborty A. Global IP6K1 deletion enhances temperature modulated energy expenditure which reduces carbohydrate and fat induced weight gain. Mol Metab. 2017;6:73-85 pubmed publisher
Edgett B, Bonafiglia J, Baechler B, Quadrilatero J, Gurd B. The effect of acute and chronic sprint-interval training on LRP130, SIRT3, and PGC-1? expression in human skeletal muscle. Physiol Rep. 2016;4: pubmed publisher
Ahuja A, Jodkowska K, Teloni F, Bizard A, Zellweger R, Herrador R, et al. A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nat Commun. 2016;7:10660 pubmed publisher
product information
Catalog Number :
AB3242
Subcategory :
Epigenetics & Nuclear Function
Product Name :
Anti-PGC-1 Antibody
Product Type :
Antibodies
Clonality :
Polyclonal Antibody
Gene ID :
O70343
Host Name :
Rabbit
Antigen :
PGC-1
Conjugate :
Affinity Purified
Product Description :
Anti-PGC-1 Antibody
Cross Reactivity :
Human;Mouse
Background :
PGC-1 is a transcription factor that determines whether preadipocytes will differentiate into brown or white fat cells. It interacts with PPARgamma to promote the expression of a cassette of genes which define the brown adipocyte phenotype.
ALT Names :
PPARgamma Coactivator 1
Immunogen :
Synthetic peptide from amino acids 777-797 (C-terminus) of mouse PGC-1
Specificity :
Specific for PGC-1 (PPARγ Coactivator 1). No cross reactivity with other proteins detected. The antibody binding has been inhibited by pre-incubating the antibody with the peptide immunogen.
Package Size :
100 μl
Uses :
ELISA;Immunocytochemistry;Western Blotting
Storage :
Stable for 1 year at -80ºC from date of receipt.
more info or order :
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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