Fractin Antibody, CT | EMD Millipore AB3150 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Fractin Antibody, CT

catalog :

AB3150

quantity :

100 µL

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Catalog Number :

AB3150

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Fractin Antibody, CT

Product Type :

Antibodies

Clonality :

Polyclonal Antibody

Gene ID :

P60709

Host Name :

Rabbit

Antigen :

Fractin

Conjugate :

Serum

Product Description :

Anti-Fractin Antibody, CT

Cross Reactivity :

Human;Mouse;Rat

Background :

During apoptosis, beta actin is cleaved by activated caspase 3 between Asp244 and Gly245. This cleavage results in the release of an approximately 130 amino acid (15 kDa) fragment from the C-terminus of beta actin and a 32 kDa (244 amino acid) N-terminal fragment of actin, known as Fractin. The C-terminus of the Fractin fragment represents an apoptosis-specific neoepitope that is not antigenic in native full-length beta actin and therefore presents a novel and specific marker for distinguishing apoptotic from necrotic cells.

ALT Names :

32 kDa Fragment of beta-Actin

Immunogen :

K-YELPD peptide representing the last five amino acids of the C-terminus of the 32 kDa Fractin fragment of beta-Actin. This sequence is absolutely conserved in Fractin fragments from human, mouse, rat, feline, porcine, ovine, bovine, canine, rabbit and guinea pig origin.

Specificity :

By immunohistochemistry and Western blot, this antibody only recognizes the 32 kDa Fractin fragment but not full-length beta actin.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Immunohistochemistry (Paraffin)

Storage :

Aliquot and store at -20°C for up to 12 months from date of receipt. Avoid repeated freeze-thaw cycles.